Veröffentlicht am

PCT - Post-Cycle-Therapie

Die Post-Cycle-Therapie ist eine Kombination von Medikamenten, die zur Verringerung der Nebenwirkungen von Steroiden eingesetzt werden. PCT ist ein Muss bei hohen Dosen, Langzeitzyklen oder Steroidkombinationen.

 

PCT-Effekte

  • Stellt den hormonellen Hintergrund wieder her
  • Erhält die gewonnene Muskelmasse
  • Verhindert Gynäkomastie
  • Verhindert die Atrophie der Hoden
  • Reduziert andere Nebenwirkungen

Hauptbestandteile der Post-Cycle-Therapie

OmatRomatase-Hemmer (Létrоzоlе, Аnаstrоzоlе usw.) - Sie werden während des Zyklus eingenommen, um östrogenbedingte Nebenwirkungen leicht aromatisierbarer Steroide (osterestosterоne, Sustаnone, МethannDrostenolon und so weiter).

Blocker des Östrogenrezeptors (Tamoxifen, Clomifen) - Sie werden nach dem Zyklus 2-3 Wochen lang eingenommen, um die natürliche Testosteronproduktion wiederherzustellen. Ihre Verwendung ist ein Kern von PCT, daher sollten Sie es nach dem Zyklus jeder Komplexität nehmen.

Chinesischer Gönner - Verhindert die Atrophie der Hoden. Normalerweise begleitet es schwere Zyklen, die länger als sechs Wochen dauern. Sie sollten in der 2-4. Woche eines Zyklus mit der Einnahme beginnen und fortfahren, bis Ihr Steroid vorbei ist, und dann mit der Einnahme von Östrogenrezeptorblockern beginnen.

Kabergolin (Déstinéx) ist eine Hemmung der Prolactinproduktion. Es begleitet die Zyklen mit Steroiden, die den Prolaktinspiegel erhöhen (Nāndrôlone, Тrénbоlone). Die übliche Dosierung beträgt 0,25 mg alle 4 Tage während Ihres Zyklus.

Itidditiоnаl cоmpоnеnts

Testen Sie einen Booster Stellen Sie die Hormonspiegel Ihres Körpers wieder her. Ihre Verwendung beginnt am Ende der Steroidaufnahme und dauert noch 2-3 Wochen (verringern Sie die Dosierung allmählich).

Hepato-schützende Substanzen - Verringerung der hepatotoxischen Wirkung einiger Steroide. Beginnen Sie mit der Einnahme in der 2. Woche eines Zyklus und fahren Sie drei weitere Wochen nach dem Ende eines Zyklus fort.

Оmеgа-3-Fettsäuren Normalisieren Sie den Chlesterolspiegel und verhindern Sie so Herz-Kreislauf-Probleme. Sie sollten sie während Ihres Zyklus und zwei weitere Wochen danach einnehmen.

Wachstumshormon und andere Peptide kann Ihnen helfen, die gewonnene Muskelmasse zu halten, auch Angstzustände, Depressionen und kardiovaskuläre Nebenwirkungen von Steroiden zu reduzieren.

Cortisоl blöken - Diese Medikamente unterdrücken den Katabolismus und helfen, die Muskeln vor Zerstörung zu bewahren. Nehmen Sie sie am Ende Ihres Zyklus und fahren Sie noch 3 Wochen fort. Es gibt jedoch keine hochwirksamen Medikamente in dieser Gruppe.

Beachten Sie, dass Prоviron nicht die optimale Substanz für PCT ist. Alle oben genannten Substanzen sind miteinander kompatibel.

Beispiele für die Post-Cycle-Therapie

Es gibt verschiedene PCT-Schemata, jedoch sind einige Merkmale gemeinsam. Beachten Sie, dass Östrogenblocker nur nach Beendigung der Steroidwirkung eingenommen werden. Die Dauer der PCT kann zwischen zwei und fünf Wochen variieren, was von der Hypophysenunterdrückung abhängt.

Clomifen (Tage - Dosierung).

3-150 / 12-100 / 15-50 / 15-25 - für einen sehr schweren Zyklus.

15-100 / 15-50 / 15-25 schwerer Zyklus.

30-50 / 15-25 - mittlerer Zyklus.

15-50 / 15-25 / 15-25 (alle zwei Tage) - Lichtzyklus.

15-50 / 15-25 – Оxаndrоlоnе, Méthāndrоstеnolone, Méthénólоne, StаnоzоlolТuranabol

Тоrеmifеne (Tage - tun)

3-120 / 12-60 / 15-30 / 15-15 - für einen sehr schweren Zyklus.

15-60 / 15-30 / 15-15 - schwerer Zyklus.

30-30 / 15-15 - mittlerer Zyklus.

15-30 / 15-15 / 15-15 (alle zwei Tage) - Lichtzyklus.

15-30 / 15-15 - andxandrolon, Мethandrostenolon, henethenolon, Stаnоzоlоl, оrāl Тurinabol.

Таmоxifen (Tagesdosis) - NEHMEN SIE ES NICHT NACH Nandrolon und Bolrenbolon Fahrräder!!!

3-80 / 12-40 / 15-20 / 15-10 - für ein sehr schweres Fahrrad.

15-40 / 15-20 / 15-10 - schwerer Zyklus.

30-20 / 15-10 - mittlerer Zyklus.

15-20 / 15-10 / 15-10 (alle zwei Tage) - leichtes Eis.

15-20 / 15-10 - andxandrolon, Мethandrostenolon, Мethenolon, Stаnоzоlоl, orales Тurinаbоl.

Andere Komponenten:

Cаbergolin (Dostinex) zur Verringerung des Proteinspiegels nach Nondrólóné- und Resinból-Zyklen (0,25 mg einmal alle vier Tage, während 1,5 Monaten).

Außerdem: Vitamin E - 200-400 IE pro Tag im 1. Monat der PCT, Zink - 50 mg / Tag.

PCT von Dr. Мiсhаеl Sсаlly

1-20 Tage: 10 HCG-Injektionen von 2000 IE, jeden zweiten Tag vor dem Schlafengehen.

1-30 Tage: Medium (Cliphencitrat), 50 mg, 2-mal täglich.

1-45 Tag: Nolvadex (Tamoxifencitrat), 20 mg, 2-mal täglich.

Dies ist das effizienteste Schema. Die Behandlung beginnt nach dem Ende eines Zyklus. Wenn Sie jedoch während Ihres Zyklus HCG eingenommen haben, ist die Verabreichung von HCG nicht erforderlich, da die Funktion der Hoden normal sein sollte.

Alternative Version von PCT

Die P ost Cycle-Therapie beginnt, wenn die Wirkung des Steroids abgeschlossen ist. Daher müssen Sie auf seine Halbwertszeit achten.

Leichte PCT (1 oder 2 Medikamente).

Amoxifen 20 Tage - 20 mg + 15 Tage - 10 mg

IfLomifen 20 Tage - 50 mg + 15 Tage - 25 mg

Starke PCT (1 oder 2 Medikamente).

Amoxifen 20 Tage - 30 mg + 15 Tage - 20 mg + 10 Tage - 10 mg

IfLomifen 20 Tage - 100 mg + 15 Tage - 50 mg + 10 Tage - 25 mg

Sehr starkes PCT (alle Medikamente).

Oxamoxifen - 20 Tage - 30 mg.

OmLomifen - 20 Tage - 100 mg. + 15 Tage - 50 mg + 10 Tage - 25 mg.

Hinweis: Verwenden Sie kein oxamoxifen, wenn Ihr Zyklus Prolaktin-induzierende Substanzen enthält.

Beispiel eines Zyklus mit PCT

Beachten Sie, dass Aromatasehemmer nicht nur Gynäkomastie verhindern, sondern auch die Testosteronkonzentration erhöhen. Dies geschieht aufgrund der Blockierung der Testosteronumwandlung in Östrogen.

Gonadotropin bewahrt die Empfindlichkeit der Hoden gegenüber endogenen gonadotropen Hormonen, was eine viel schnellere Erholung nach dem Zyklus ermöglicht.

Tamoxifen ist ein Schlüsselelement der Post-Zyklus-Therapie. Es initiiert die Sekretion von endogenem Testosteron, indem es die Östrogenrezeptoren in der Hypophyse blockiert, jedoch sind mlоmiphéné und Тorémifen besser bevorzugt.

Wachstumshormon und Peptide sind gut für die Unterdrückung von Katabolismus.

Beispiel eines Progestin-Zyklus

Einige Steroide wie Deca, bolrenbolon können den Prolaktinspiegel erhöhen, was zu einer verminderten Libido, Wasserretention und Prolaktin-induzierter Gynäkomastie führt. Cabergolin kann diese Nebenwirkungen vollständig verhindern.

Sie können Clomid anstelle von Tamoxifen oder einem sichereren Medikament - Toremifen - verwenden.

Veröffentlicht am

Top 6 Tipps zur Tierpflege für Ihren Hund

Unabhängig davon, ob Sie planen, Ihren ersten Hund zum ersten Mal zu kaufen oder bereits einen zu erziehen, müssen Sie sich um Ihren geliebten vierbeinigen Freund kümmern, indem Sie seine geistige und körperliche Gesundheit im Auge behalten.

Wenn Ihr Hund bereits an einer chronischen Krankheit leidet und Steroide und Meditationen dafür einnimmt. Sie müssen sicherstellen, dass Ihr Haustier seine Medikamente regelmäßig in der vorgeschriebenen Dosierung einnimmt. Hundepflege ist unvollständig, wenn Sie Ihrem Haustier nicht Ihre Zeit, bedingungslose Liebe und Zuneigung geben.

Wenn Ihr Haustier Steroide hat und an Allergien oder chronischen Krankheiten leidet, ist es noch wichtiger, sich gut um Ihr Haustier zu kümmern.

In diesem Artikel werden wir einige wichtige Möglichkeiten diskutieren, wie Sie Ihr Haustier gut pflegen können.

Sorgen Sie für eine saubere und tierfreundliche Umgebung für Ihren Hund

Um eine saubere und gesunde Umgebung für Ihre Haustiere zu schaffen, müssen Sie Ihr Haustier zunächst vor Luftverschmutzung in Innenräumen und anderen potenziell schädlichen Schadstoffen schützen, die in Innenräumen vorhanden sind. Bei warmem oder feuchtem Wetter können Sie Klimaanlagen oder Kühler verwenden, um die Luft zu reinigen.

Halten Sie Ihr Haustier kühl und hydratisiert

Wie bereits erwähnt, müssen Sie, wenn Ihr Haustier Steroide oder Meditationen hat, noch mehr auf die tägliche Ernährung Ihres Haustieres achten. Einige häufige Nebenwirkungen von Medikamenten und Steroiden bei Hunden sind erhöhter Durst, Durchfall und Urinieren. All diese Nebenwirkungen können bei Hunden zu Dehydration führen. Durch ständige Dehydration kann sich Ihr Hund besonders in den Sommermonaten schwach und müde fühlen. Daher müssen Sie sicherstellen, dass Ihr Hund die richtige Menge Wasser pro Tag trinkt. Versuchen Sie, Ihrem Haustier frisches und sauberes Wasser zu geben, indem Sie das Wasser wechseln und die Wasserschale sauber und hygienisch halten.

Kümmern Sie sich um die Ernährungsbedürfnisse Ihres Hundes

Fettleibigkeit kann die allgemeine Gesundheit und Fitness Ihres Haustieres erheblich beeinträchtigen. Vermeiden Sie Fettleibigkeit bei Ihrem Haustier, indem Sie die Ernährungsempfehlungen des Tierarztes befolgen. Idealerweise ist es am besten, wenn Sie Ihren Hund nach Größe, Rasse, Lebensstil, Alter und körperlicher Aktivität füttern. Versuchen Sie, sich für Bio-Tiernahrung für Ihren Hund zu entscheiden. Wenn Ihr Hund gegen Futtermittel wie Mais, Rindfleisch, Milchprodukte oder Geflügelprodukte allergisch ist, vermeiden Sie den Kauf von Tiernahrung, die Allergien auslösen kann. Stellen Sie sicher, dass Sie ihm gesunde Leckereien geben, anstatt Ihre eigenen Mahlzeiten als Belohnung mit ihm zu teilen.

 

Überspringen Sie keine regelmäßigen Tierarztuntersuchungen

Ihr örtlicher Tierarzt kann Ihnen alle notwendigen Informationen bezüglich der Impfung und Entwurmung Ihres Hundes geben. Stellen Sie sicher, dass Sie immer ein oder zwei Kopien des Impfprotokolls Ihres Hundes bei sich haben, insbesondere wenn Sie mit Ihrem Haustier in eine neue Stadt oder ein neues Land reisen. Speichern Sie die Nummer Ihres Tierarztes in Ihrem Telefon, um ihn zu kontaktieren, falls es Ihrem Hund nicht gut geht.

Halten Sie Ihr Haustier körperlich aktiv und geistig stimuliert

Stellen Sie sicher, dass Sie Zeit mit Ihrem Haustier verbringen, um seinen Geist frisch und angeregt zu halten. Sie können mit Ihrem Haustier lustige Aktivitäten ausführen, z. B. einen kurzen Spaziergang machen oder seine hausgemachten Lieblingsleckereien zubereiten. Stellen Sie sicher, dass Sie seine Pfoten reinigen, nachdem Sie von einem Spaziergang nach Hause gekommen sind. Vermeiden Sie es außerdem, sich Ihrem Hund zu nähern, wenn Sie sich nicht wohl fühlen und an Grippe oder fieberartigen Symptomen leiden. Sie können jeden in Ihrer Familie oder Ihren Nachbarn bitten, Ihren Hund für Sie zu füttern. Wenn Sie Zeit mit Ihrem Hund verbringen, verstehen Sie die Vorlieben, Abneigungen, Verhaltensmuster usw. Ihres Haustieres.

Kümmern Sie sich um die Pflege und Hygiene Ihres Haustieres

Mundhygiene ist ein wesentlicher Bestandteil der Tierpflege. Viele Hunde haben ein schwaches Zahnfleisch, und wenn die richtige Mundgesundheit nicht erhalten bleibt, kann dies zu Mundinfektionen oder Zahnverlust führen. Lange und überwachsene Nägel können es älteren Hunden schwer machen, richtig zu gehen. Darüber hinaus neigen lange Nägel dazu, schwach zu sein und schnell aufzubrechen, was sehr schmerzhaft sein kann.

Um zusammenzufassen

In diesen stressigen Zeiten, in denen Menschen aufgrund des Koronaausbruchs in ihren Häusern eingesperrt sind, müssen Sie besonders auf die körperliche Fitness Ihres Haustieres achten. Viele Tierhalter vermeiden es, ihre Hunde in öffentliche Parks zu bringen, und bleiben lieber drinnen, um eine Infektion mit dem Coronavirus zu verhindern. Um Ihr Haustier körperlich fit und aktiv zu halten, können Sie es daher auf dem Rasen oder im Garten Ihres Hauses spielen lassen.

Veröffentlicht am

Beste Bulking Sarms

Each of Selective Androgen Receptor Modulators (SARMs) has unique properties. Here we’ll discuss most popular ones and their benefits:

Ostarine (MK-2866) optimal for novices

Ostarine is an incredibly dynamic SARM which can prevent loss of muscles. It is good for those who suffer from lack of calories during drying cycles, as they can burn fat without reduction of muscle mass.

Due to its properties, ostarine is often used in medical practice for treatment of muscle loss in patients. However, athletes mainly use it for boosting strength and stamina and for prevention of muscle loss.

Usually ostarine cycle lasts for 8 weeks. The dose varies from 10 mg to 25 mg, and it’s better not to exceed it since it may suppress HPTA.

Radarine (RAD-140) – possibly one of the most powerful SARMs

Radarin, aka RAD-140, is rather new drug, but it gained popularity for fast results with low sides. It is mainly used for increasing muscle mass and strength, and is suitable for cutting and bulking cycles.

It can provide huge increase in strength, which can help you to overcome yourself. It also boosts energy thus you can do workouts for much longer.

Ligandrol (LDD-4033) – perfect for bulking

Ligandrol is mostly taken for bulking and is preferred for its long half-life, which is about 1-1,5 days, therefore you can take it only once a day. It is also famous for low sides and as a powerful fat burner.

 

Cardarin (GW501516) perfect for cutting

 

Cardarine is used for increasing endurance and as a fat burner. It also reduces bad cholesterol in the blood. In medicine it is used to protect cerebral blood vessels from damage and stress, as well as to fight obesity.

 

Best SARM cycles for Cutting

MK-2866 Ostarine 20 mg / day along with Cardarine 10 mg / day for 2.5 months. This combo is perfect for keeping muscle mass, fat-burning, and endurance.

MK-2866 Ostarine 20 mg / day along with LGD-4033 Ligandrol 10 mg / day for two months. This combo can help you to increase muscle volume and to avoid of muscle loss.

SARM cycles for bulking

LGD-4033 Ligandrol 10 mg / day along with RAD140 10 mg for 2 months cycle. It provides fast bulking, with very low sides.

S23 10 mg, RAD-140 10 mg and Ibutamoren 20 mg / daily for an 2 months cycle. It can help you to gain mass extremely fast. Ibutamoren also boosts Growth Hormone levels which has additional benfits.

Best SARM cycles for cutting

LGD-4033 Ligandrol 10 mg in combo with GW501516 cardarin 10 mg daily for an 2 months cycle. This combo is powerful fatburner and also reduces water retention, besides it lowers bad cholesterol in the body.

Best SARM cycles for strength

RAD140 – 10 mg and S23 at 10 mg / day for 2 months cycle. This combo is perfect for muscle gaining and can be incredibly beneficial for power and strength.

YK-11 10 mg and LGD-4033 10 mg for 2 months. This combo is exceptional for increasing pure strength and muscle mass with low sides.

 

In order these SARMs to work effectively, one should train properly and combine the cycles with healthy habits and lifestyles. Also do not forget to eat proteins every day, especially after workout.

Veröffentlicht am

Anastrozol Bodybuilding

Anastrozole is an aromatase inhibitor. In simple terms, it blocks functioning of aromatase enzyme, which is responsible for converting testosterone to estradiol. The drug is used during cycle with aromatizable anabolic steroids to reduce the negative effects of estrogen on the body.

Initially we should discuss the positive and negative effects of estrogen on the male body. Estrogens play an important role in various functions of the male and female body. The general health of the athlete and his results depend on these very functions.

Positive Effects of Estrogens:

  • play an important role in the immune system;
  • necessary in the nutrition of bone tissue;
  • have a positive effect on cholesterol levels;
  • necessary for the production of growth hormone (GH) and insulin-like growth factor (IGF);
  • play an important role in maintaining the “fluid balance” in the body at the proper level;
  • help to absorb glucose;
  • support sex drive.

Negative aspects of increased estrogen levels:

  • retain fluid in the body, swelling;
  • fatigue and increased muscle blockage during training;
  • acne that has not been previously observed;
  • the risk of prostate cancer increases;
  • blood clotting increases;
  • the risk of cardiovascular disease increases;
  • the risk of hypertension (high blood pressure) increases;
  • the risk of stroke increases;
  • cause gynecomastia (swelling and itching in the nipple area, breast enlargement);
  • decreased sexual desire;
  • female obesity;
  • extra sweating;
  • possible sleep disturbances;
  • can provoke hair loss;
  • possible disturbances in the work of the gastrointestinal tract.

 

With the help of aromatase inhibitors, the level of estrogens is controlled. The competent use of anastrozole allows not only to counteract aromatization, but also to simultaneously increase the level of free testosterone. If you follow the dosage regimen, the agent will be perfectly tolerated by the body, without any negative effects.

The drug Anastrozole was invented at the end of the last century, its original purpose – the treatment of breast cancer. The effectiveness of the drug in this area has been proven, this contributed to its popularity in sports when using anabolic steroids by athletes.

Anastrozole in bodybuilding is used when the athlete begins to use anabolic steroids, which prone to aromatization, such as testosterone and danabol. This steroids may cause gynecomastia. In simple terms, this is the growth of the mammary gland. That is why many athletes take anastrozole during steroid cycles.

It suppresses the enzyme, interfering with the destruction of testosterone and the production of estrogen. The main effect of anastrozole is:

  • prevention of fluid retention;
  • suppression of the production of female hormones;
  • stimulation of natural testosterone production;
  • prevention of testicular atrophy;
  • increased libido in men;
  • prevention of gynecomastia;
  • improving muscle tone;
  • an increase in the level of anabolic hormones in the blood;
  • prevention of hypertension.

To avoid serious side effects on the testosterone and danabol cycle, anastrozole should be used immediately. It is easier to prevent the development of serious diseases than to cure them.

Possible side effects of anastrozole

Any medicine has both positive effect and negative one. Problems can arise if the athlete exceeds the recommended dose or takes the drug for too long. For the normal functioning of the male body, estrogens are necessary. If you take anastrozole for a long time and uncontrollably on the cycle of anabolic steroids, the level of this hormone can reach critically low levels.

This can cause a number of side effects:

  • memory impairment,
  • apathy, drowsiness,
  • fatigue;
  • frequent mood swings up to depression;
  • violation of oxygen metabolism in tissues;
  • deterioration of blood clotting;
  • violation of the functionality of nerve cells;
  •  joint pain;
  • decreased bone strength (osteoporosis);
  • headache, dizziness;
  • decreased libido;
  • low sperm motility;
  • increase in blood cholesterol levels;
  • anemia, thromboembolism, thrombophlebitis;
  • skin rashes and itching;
  • thinning hair, baldness;
  • lack of appetite while gaining weight;
  • liver disease.

All this suggests that anastrozole in bodybuilding should be used with caution, blood counts should be monitored, and the recommendations of professionals should be followed.

How to use anastrozole on the cycle of anabolic steroids?

If you don’t use aromatizable steroids, then you probably won’t need the drug. And if you do steroid cycle with testosterone, then you cannot do without anastrozole.

It can be used even before the cycle of anabolic steroids in case your level of aromatization is increased, as can be seen from the analyzes. You do not need to take this drug at random. Anastrozole is also used during PCT to reduce the level of aromatization, if this occurs and is monitored by tests for Estradiol.

Anastrozole can be taken at any time of the day, but the maximum effect can be achieved when taken on an empty stomach. If you drink a medicine with plenty of water, it will be absorbed faster and penetrate into the bloodstream. When using testosterone, anastrozole is taken both on different days and every day, it all depends on your level of aromatization, which proceeds differently for everyone due to individual characteristics, as well as depending on the dosage of testosterone and its ester.

You should take Anastrozole during the whole period of steroid action. For example, when using testosterone propionate, anastrozole must be taken up to the fifth day after the last injection. And after long estered testosterones (enanthate, decanoate, cypionate, sustanon, etc.), anastrozole has to be taken for the third week after the last injection, and sometimes longer.

If you take steroids with a short half-life (methandrostenolone), then start taking anastrozole with a lower dosage and frequency (0.5 mg three times a week or every other day). After 15-20 days of administration, the blood test should be repeated.

When using testosterone propionate, for example, 100 mg. / every other day, the dosage of anastrozole can be 0.5 mg every other day, or every day 0.5 mg, or 1 mg every day, and the last intake of anastrozole should be on the fifth day after the last injections.

If you are using long-ester steroids, then start taking anastrozole few days after the first injection, and after two to three weeks check with the aim of adjusting the dosage, and the subsequent recheck should be done at least once a month.

It is important to carefully monitor your body in order to timely determine the imbalances in the hormonal background and timely prevent the occurrence of side effects, changing the frequency of taking accompanying drugs, up to their cancellation.

 

During post-cycle therapy, anastrozole is not used if the level of aromatization is not rises above the permissible values. It is not permissible to replace anastrozole with tamoxifen, since they have mutually exclusive effect.

Veröffentlicht am

Bodybuilder Insulin

Insulin in bodybuilding

Why is insulin needed and how does it work?

Insulin is a peptide hormone, formed in the beta cells of the islets of Langerhans of the pancreas. It has a multifaceted effect on metabolism in almost all tissues. The main action of insulin is to lower the concentration of glucose in the blood. In bodybuilding, insulin is used due to its pronounced anabolic effect.

Insulin increases the permeability of plasma membranes for glucose, activates key glycolysis enzymes, stimulates the formation of glycogen from glucose in the liver and muscles, and enhances the synthesis of fats and proteins. In addition, insulin inhibits the activity of enzymes that break down glycogen and fats. That is, in addition to the anabolic effect, insulin also has an anti-catabolic effect.

The transport of glucose in two types of tissues depends to the greatest extent on insulin: muscle tissue and adipose tissue – this is the so-called. insulin-dependent tissues.

Insulin effects

  • increased absorption of glucose and other substances by cells;
  • activation of key glycolysis enzymes;
  • an increase in the intensity of glycogen synthesis – insulin accelerates the storage of glucose by liver and muscle cells by polymerizing it into glycogen;
  • a decrease in the intensity of gluconeogenesis – the formation of glucose in the liver from various substances of a non-carbohydrate nature (proteins and fats) decreases.

Anabolic action of insulin

  • enhances the absorption of amino acids by cells (especially leucine and valine);
  • enhances the transport of potassium ions into the cell, as well as magnesium and phosphate;
  • enhances DNA replication and protein biosynthesis;
  • enhances the synthesis of fatty acids and their subsequent esterification – in adipose tissue and in the liver, insulin promotes the conversion of glucose into triglycerides; with a lack of insulin, the opposite occurs – the mobilization of fats.

Insulin anti-catabolic action

  • inhibits protein hydrolysis – reduces protein degradation;
  • reduces lipolysis – reduces the flow of fatty acids into the blood.

The Dangers of Using Insulin

Perhaps the main factor in insulin’s bad reputation is the risk of hypoglycemia. On any forum, you can find messages of a warning nature, as if even a slight excess of the dose of insulin could be fatal. However, scientific and practical evidence suggests otherwise: the lowest lethal dose of insulin is 100 U, that is, a full insulin syringe. Many people survive even after 3000 IU doses! But in the event of a serious insulin overdose, there is no time to call an ambulance in a clear consciousness. Depending on the degree of overdose, it takes from several minutes to several hours to the development of a coma, so even lethal doses of insulin do not cause death if the timely flow of glucose into the blood begins.

What insulin is used in bodybuilding

In bodybuilding, short-acting and ultra-short-acting insulin should be used:

Short-acting insulin

Short insulin begins to act when injected subcutaneously after 30 minutes (therefore, it is administered 30-40 minutes before meals), the peak of action occurs after 2 hours, disappears from the body after 5-6 hours.

The best choice:

  • Humulin Regular
  • Actrapid HM

Ultra-short-acting insulin

Ultra-short insulin begins to act in 0-15 minutes, peak in 2 hours, disappear from the body in 3-4 hours. It is more physiological and can be administered immediately before a meal (5-10 minutes) or immediately after a meal.

The best choice:

  • Insulin aspart (NovoRapid Penfill, NovoRapid FlexPen).
  • Insulin lispro (Humalog)
  • Insulin glulisine (Apidra) are all semi-synthetic analogs of human insulin.

Advantages and Disadvantages of Insulin

Benefits:

  • Low cost of the cycle
  • Availability – the drug can be purchased freely at the pharmacy
  • High quality – counterfeits are practically excluded, unlike steroids
  • Lack of toxicity, low frequency of side effects, almost complete absence of the consequences of the course
  • Pronounced anabolic effect
  • Can be combined with anabolic steroids and other drugs
  • Lack of androgenic effects
  • Insulin DOES NOT have a toxic effect on the liver or kidneys, and also DOES NOT CAUSE sexual dysfunction.

Disadvantages:

  • Complex reception scheme
  • Significant fat gain
  • Hypoglycemia

Nebenwirkungen

Hypoglycemia or a decrease in the concentration of glucose in the blood, which entails all other manifestations. Hypoglycemia can be easily prevented, read about it in the main article – Hypoglycemia.

Itching in the area of ​​the injection

Allergy – extremely rare

Decreased endogenous insulin secretion – occurs only with very long courses with high doses of insulin

A decrease in endogenous insulin secretion occurs only during exogenous use of insulin (duration of action of short-acting or ultra-short-acting insulin). Insulin, unlike other endocrine hormones, is not regulated by the hypothalamic-pituitary system and does not have a feedback principle. The only stimulators of insulin synthesis are the level of glycemia and food intake (through the mechanism of the secretin cascade). Therefore, even a very long-term use of insulin does not change its secretion, after its withdrawal. But this is not a positive quality of the use of this hormone, since the risk of developing hypoglycemic conditions is very high !! To stop hypoglycemia, it is necessary to use fast carbohydrates, and since short or ultrashort insulin is used, all fast carbohydrates entering the bloodstream are carried away in the process of lipogenesis in adipose tissue. Excessive use of insulin, its “overdose” leads to an increase in fat reserves. As an anabolic hormone, it is weak, but hypoglycemia leads to the release of growth hormone, which has an anabolic effect.

 

Veröffentlicht am

Was ist Sustanon?

Sustanon – testosterone mix

Testosterone is need for the successful functioning of hormonal levels, metabolic processes and the immune system in men. Low testosterone levels negatively affect sexual activity, reduce muscle mass, and contribute to the development of depression.

The initial goal of Sustanon was correction of testosterone levels in men, therefore it was included into the list of drugs used for hormone replacement therapy. But over time, athletes and professional bodybuilders drew attention to its properties. It has been used successfully as an anabolic steroid since the 1970s. Today, many athletes decide to buy Sustanon 250, for whom it is important to increase body weight without negative consequences for the body.

 

Structure

Sustanon 250 consists of four testosterone esters: propionate, phenylpropionate, isocapronate, decanoate. The composition also includes auxiliary substances: peanut oil as a solvent and benzyl alcohol as an antiseptic. All four forms of testosterone in the composition of the drug have their own period of action, which increases the effectiveness of the drug.

Sustanon properties and benefits

The high effectiveness and prolonged action of Sustanon makes frequent use unnecessary. Even one injection already provides a positive result. With a rare intake schedule, it is possible to maintain testosterone at the required level.

 

The main advantages of the product include:

  • ensuring the optimal level of hormone concentration;
  • a rapid increase in muscle mass;
  • improved metabolism;
  • activation of blood circulation processes;
  • anticatobolic effect by reducing the level of cortisol in the blood;
  • increase in the number of red blood cells in the blood;
  • increased sexual activity.

 

Contraindications and side effects

Testosterone injections should not be given for established or suspected prostate cancer. Sustanon 250 should be taken with caution by persons with epilepsy, heart failure, arterial hypertension, since prolonged use can cause complications. But in most cases, side effects occur against the background of improper intake of the drug or a significant excess of the permissible dosage.

 

Among the negative consequences should be highlighted:

  • female type fat accumulation;
  • increased blood cholesterol levels;
  • excessive hair loss, baldness;
  • acne;
  • painful sensations at the injection site;
  • increased blood pressure;
  • insomnia, depressed mood, unreasonable aggressiveness.
  • In rare cases, symptoms of gynecomastia in men and prostate hypertrophy are possible.

Taking the drug by women can cause menstrual irregularities, coarsening of the voice, deterioration of ovarian activity.

 

How to take Sustanon correctly

Correct intake of the drug allows you to reduce the risk of side effects to a minimum. Start with a weekly injection at a dosage of 250 mg / week intramuscularly. Injections are best done in the buttocks area. In the future, the dosage is increased and brought to 1000 mg / week. The maximum duration of cycle is 10 weeks. The duration of action is 5-6 days.

Interaction with other steroids

The injections of the product can be taken both solo and in combination with other drugs. The combination with nandrolone promotes the growth of muscle fibers, and the combination with Winstrol has a positive effect on drying. Combinations with such drugs as Turinabol, Boldenone and others are also possible.

Veröffentlicht am

Arimidex-Dosierung während des Zyklus

Arimidex (Anastrozole) is an aromatase inhibitor, an enzyme that converts testosterone to estradiol. When used with anabolic drugs, Anastrazole minimizes the side effects of estrogen.

Anastrazole controls the level of this female sex hormone, it also increases the levels of free testosterone. The drug is safe and well tolerated when correct doses are used.

  • Reduces estrogen levels
  • Increases the effectiveness of steroid hormones.
  • Promotes natural testosterone synthesis even with androgen steroids.
  • Prevents gynecomastia in men.

Pharmacodynamics

The non-steroidal active ingredient selectively blocks aromatase. In postmenopausal women, folliculin, androstenedione and aromatase promote estradiol synthesis.

With a decrease in the estradiol level, breast cancer is treated. The estradiol level is reduced by 80%. The drug has no progestogenic, estro or androgenic activity.

When the tablets are taken orally, the active substance is rapidly absorbed from the gastrointestinal tract. Its binding to plasma proteins will be 40%. Accumulation in the body does not occur. The maximum concentration in the blood will reach after 2 hours if the agent is taken on an empty stomach.

Dealkylation, hydroxylation, glucuronidation ensure the absorption of the drug by the liver. Urine and blood contain the main metabolic product, triazole. Excretion of drug metabolites is 3 days.

Benefits and harm

  • Anastrozole removes unnecessary fluid from the body.
  • It has a positive effect on blood cholesterol profile.
  • Increases libido in men.
  • Prevents arterial hypertension.
  • Decreases estrogen dependent inhibition of the pituitary-hypothalamus-testicles axis.
  • The remedy is popular for PCT during the recovery period.
  • The medicine helps well with hormone replacement therapy.

One should remember that estradiol is needed by the body for normal functioning. Therefore, it is important for an athlete to remember about biological role of estradiol and to keep it on the proper level.

 

The low estrogen levels may cause

  • Memory impairment
  • Mood changes
  • The problems with joints
  • Depression.
  • Decreased Libido.
  • The cholesterol level will rise.

 

How to take it right

The tablets are indicated for bodybuilders with experience after a cycle of anabolic steroids at maximum dosages. The medicine is used in two cases: before the cycle of anabolic steroids for prophylaxis with therapeutic doses, and after the cycle, to prevent the side effects of steroids.

The tablets should be taken on an empty stomach with a large volume of water. In this case, the active ingredient will quickly enter the bloodstream from the digestive system.

On the cycle, Anastrozole should be taken every other day during 2 weeks. The optimal dosage for good athletic performance does not exceed 250 mcg once every 2 days.  To reduce the estardiol level by half, a dose of 0.5-1 mg is recommended. For preventive measures in bodybuilding, 0.5 mg is enough every other day.

For gynecomastia 1 mg is used until the symptoms are eliminated, then 0.5 mg every other day. It is important to remember that not all anabolic steroids are aromatized. For example, in Anadrol, the transformation into estrogens is insignificant.

When using anabolic steroids with a short half-life, like Methandrostenolone, after 10 days, an analysis is made for the concentration of estradiol in the blood, Anastrozole is taken at 0.5 mg every other day. Then, after 10 days, estradiol is examined, the dose is adjusted.

When using anabolic steroids with long esters, for example, Sustanon, the dosage is 0.5 mg every other day. It is required to make a test for estradiol in 3 or 4 weeks after beginning of a cycle. The control analysis is carried out approximately in 10 or 14 days after you start taking Anastrozole. You should decrease the dosage if side effects are observed.

You should not combine Tamoxifen with Anastrozole. With such drug interactions, there is a mutual weakening of these drugs. It is forbidden to consume alcohol with Anastrozole, otherwise, with such compatibility, the pharmacological effect of the drug will not appear, undesirable consequences will appear.

 

Post-Cycle-Therapie

It is important to remember that drugs that inhibit aromatase are not used in post-cycle therapy, they are used during the cycle and after the use of anabolic steroids (before PCT).

 

During PCT, drugs that block estrogen receptors (Clomid, Tamoxifen) are taken after a cycle for 2-3 weeks. Tamoxifen requires 10-20 mg per day, or Clomid 25-50 mg per day is used. The dose is gradually reduced towards the last week.

 

Thanks to chorionic gonadotropin, testicular atrophy can be prevented. It is used for heavy cycles, the duration of which is more than 6 weeks. It is introduced on the last 4-5 weeks of the cycle and should be used until discontinuation of steroids. Then you need to switch to drugs that block estrogen receptors.

 

The use of Cabergloline is recommended during cycles with progestin drugs, due to which the prolactin level increases. The dosage is 0.25 mg every 4 days for the entire cycle.