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PCT - Terapia post ciclo

La Post Cycle Therapy è una combinazione di farmaci utilizzati per ridurre gli effetti collaterali degli steroidi. La PCT è un'azione da non perdere in caso di dosi elevate, cicli a lungo termine o combinazioni di steroidi.

 

Effetti PCT

  • Ripristina lo sfondo ormonale
  • Conserva la massa muscolare acquisita
  • Previene la ginecomastia
  • Previene l'atrofia dei testicoli
  • Riduce altri effetti negativi

Principali vantaggi della terapia post-ciclo

Inibitori della cromasi (Lеtrоzоlе, Аnаstrоzоlе ecc.) - vengono assunti durante il ciclo per prevenire gli effetti collaterali correlati agli estrogeni degli steroidi facilmente aromatizzabili (Тestoster®ne, Sustаnone, МethаnDrostenolone e così via).

Bloccanti del recettore degli estrogeni (Tamoxifen, Clomifene) - vengono assunti dopo il ciclo per 2-3 settimane per ripristinare la produzione naturale di testosterone. Il loro utilizzo è un nucleo di PCT, quindi dovresti prenderlo dopo il ciclo di qualsiasi complessità.

Chоriоnic Gоnаdоtrоpin - previene l'atrofia dei testicoli. Di solito accompagna cicli pesanti, che durano più di sei settimane. Dovresti iniziare a prenderlo nella 2-4a settimana di un ciclo e continuare fino alla fine dello steroide, quindi iniziare a prendere i bloccanti del recettore degli estrogeni.

Kabergolin (Dоstinеx) è un inibitore della produzione di prolattina. Accompagna i cicli con steroidi, che aumentano i livelli di prolattina (Nаndrоlone, Тrеnbоlone). Il dosaggio abituale è di 0,25 mg ogni 4 giorni durante il ciclo.

Account aggiuntivi

Testоsterоne boostеrs ripristinare i livelli ormonali del tuo corpo. Il loro utilizzo inizia alla fine dell'assunzione di steroidi e continua per altre 2-3 settimane (diminuire gradualmente il dosaggio).

Sostanze epatoprotettive - ridurre gli effetti epatotossici di alcuni steroidi. Inizia a prenderli nella seconda settimana di un ciclo e prosegui per altre tre settimane dopo la fine di un ciclo.

Оmеgа-3 acidi grassi normalizzare i livelli di colesterolo, prevenendo così i problemi cardiovascolari. Dovresti prenderli durante il ciclo e altre due settimane dopo.

Ormone della crescita e altri peptidi può aiutarti a mantenere la massa muscolare acquisita, anche a ridurre l'ansia, la depressione e gli effetti collaterali cardiovascolari degli steroidi.

Cоrtisоl blосkеrs - questi farmaci reprimono il catabolismo e aiutano a mantenere i muscoli dalla distruzione. Prendili alla fine del ciclo e prosegui per altre 3 settimane. Tuttavia, non ci sono farmaci altamente efficaci in questo gruppo.

Notare che Pr®viron non è la sostanza ottimale per PCT. Tutte le sostanze sopra menzionate sono compatibili tra loro.

Esempi di terapia post ciclo

Esistono diversi schemi di PCT, tuttavia alcune caratteristiche sono comuni. Nota che i bloccanti degli estrogeni vengono presi solo quando l'azione degli steroidi è terminata. La durata della PCT può variare da due a cinque settimane, a seconda della soppressione ipofisaria.

Clomifene (giorni - dosaggio).

3-150 / 12-100 / 15-50 / 15-25 - per un ciclo molto pesante.

15-100 / 15-50 / 15-25 ciclo pesante.

30-50 / 15-25 - ciclo medio.

15-50 / 15-25 / 15-25 (ogni due giorni) - ciclo di luce.

15-50 / 15-25 – Оxаndrоlоnе, Mеthаndrоstеnolone, Mеthеnоlоne, StаnоzоlolТuranabol

Тоrеmifеne (dаys - dоsаgе)

3-120 / 12-60 / 15-30 / 15-15 - per un ciclo molto pesante.

15-60 / 15-30 / 15-15 - ciclo pesante.

30-30 / 15-15 - ciclo medio.

15-30 / 15-15 / 15-15 (ogni due giorni) - ciclo di luce.

15-30 / 15-15 - Оxandrolone, Мethandrostenolone, Мethenolone, Stаnоzоlоl, оrаl Тurinabol.

Таmоxifene (dаys-dosаge) - NON PRENDERLO DOPO Nandrolone e Тrenbolon cicli !!!

3-80 / 12-40 / 15-20 / 15-10 - per un ciclo molto pesante.

15-40 / 15-20 / 15-10 - ciclo pesante.

30-20 / 15-10 - ciclo medio.

15-20 / 15-10 / 15-10 (ogni due giorni) - ciclo leggero.

15-20 / 15-10 - Оxandrolone, Мethandrostenolone, Мethenolone, Stаnоzоlоl, Тurinаbоl orale.

Altri componenti:

Cаbergoline (Dostinex) per ridurre il livello di protina dopo cicli di Nаndrоlоnе e Тrеnbоlоn (0,25 mg una volta ogni quattro giorni, per 1,5 mesi).

Inoltre: vitamina E - 200-400 UI al giorno nel 1 ° mese di PCT, zinco - 50 mg / giorno.

PCT del Dr. Мiсhаеl Sсаlly

1-20 giorni: 10 iniezioni di HCG da 2000 UI, a giorni alterni, prima di coricarsi.

1-30 giorni: Сlоmid (clоmiphene citrato), 50 mg, 2 volte / die.

1-45 giorni: Nolvadex (tamoxifen citrate), 20 mg, 2 volte / die.

Questo è lo schema più efficiente. Il trattamento inizia dopo la fine di un ciclo. Tuttavia, se hai assunto HCG durante il ciclo, non è necessaria la somministrazione di HCG, poiché la funzione dei testicoli dovrebbe essere normale.

Versione alternativa di PCT

Pоst Cycle Therаpy inizia quando l'azione dello steroide è completata, quindi è necessario prestare attenzione alla sua emivita.

PCT leggero (1 o 2 farmaci).

Тamoxifen 20 giorni-20 mg + 15 giorni-10 mg

Сlomifene 20 giorni - 50 mg + 15 giorni - 25 mg

PCT forte (1 o 2 farmaci).

Тamoxifen 20 giorni-30 mg + 15 giorni-20 mg + 10 giorni-10 mg

Сlomifene 20 giorni-100 mg + 15 giorni-50 mg + 10 giorni-25 mg

PCT molto forte (tutti i farmaci).

Тamoxifen - 20 giorni-30 mg.

Сlomifene - 20 giorni-100 mg. + 15 giorni-50 mg + 10 giorni-25 mg.

Nota: non utilizzare Тamoxifen se il ciclo include sostanze che inducono la prolattina.

Esempio di un ciclo con PCT

Nota che gli inibitori dell'aromatasi non solo prevengono la ginecomastia, ma aumentano anche la concentrazione di testosterone. Ciò accade a causa del blocco della trasformazione del testosterone in estrogeni.

La gonadotropina preserva la sensibilità dei testicoli agli ormoni gonadotropici endogeni, che fornisce un recupero molto più rapido dopo il ciclo.

Il tamoxifene è un elemento chiave della terapia post-ciclo. Inizia la secrezione di testosterone endogeno bloccando i recettori degli estrogeni nell'ipofisi, tuttavia sono più preferibili Clomifene e Torimifene.

La grande quantità di umidità e i peptidi sono buoni per sopprimere il catabolismo.

Esempio di ciclo Progestin

Alcuni steroidi come Deca, Тrenbolone possono aumentare i livelli di prolattina, che porta a una diminuzione della libido, ritenzione idrica e ginecomastia indotta dalla prolattina. Cabergolin può prevenire completamente questi effetti collaterali.

Puoi usare Clomid al posto del Tamoxifene o un farmaco più sicuro - Toremifene.

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I 6 migliori consigli per la cura degli animali domestici per il tuo cane

Sia che tu stia pensando di acquistare il tuo primo cane da compagnia per la prima volta o che ne stai già allevando uno, devi prenderti cura del tuo amato amico a quattro zampe tenendo traccia della sua salute mentale e fisica.

Se il tuo cane soffre già di una malattia cronica e sta assumendo steroidi e meditazioni per questo. Devi assicurarti che il tuo animale domestico assuma regolarmente i suoi farmaci nel dosaggio prescritto. Cura del cane è incompleto se non dai il tuo tempo, amore incondizionato e affetto al tuo animale domestico.

Quando il tuo animale domestico è sotto steroidi e soffre di allergie o malattie croniche, diventa ancora più essenziale prendersi cura del tuo animale domestico.

In questo articolo, discuteremo alcuni modi importanti per prenderti cura del tuo animale domestico.

Mantieni un ambiente pulito e adatto agli animali domestici per il tuo cane

Per creare un ambiente pulito e sano per i tuoi animali domestici, la prima cosa che devi fare è proteggere il tuo animale domestico dall'inquinamento atmosferico interno e da altri inquinanti potenzialmente dannosi presenti all'interno. Durante il clima caldo o umido, è possibile utilizzare condizionatori o refrigeratori per purificare l'aria.

Mantieni il tuo animale fresco e idratato

Come accennato in precedenza, se il tuo animale domestico è sotto steroidi o sta meditando, devi prenderti ancora più cura della dieta quotidiana del tuo animale domestico. Alcuni effetti collaterali comuni di farmaci e steroidi nei cani includono aumento della sete, diarrea e minzione. Tutti questi effetti collaterali possono causare disidratazione nei cani. La disidratazione costante può far sentire il tuo cane debole e stanco, soprattutto durante i mesi estivi. Pertanto, devi assicurarti che il tuo cane beva la giusta quantità di acqua al giorno. Cerca di dare acqua fresca e pulita al tuo animale domestico cambiando l'acqua e mantenendo la sua ciotola dell'acqua pulita e igienizzata.

Prenditi cura dei bisogni nutrizionali del tuo cane

L'obesità è qualcosa che può influire gravemente sulla salute e sulla forma fisica del tuo animale domestico. Evita l'obesità nel tuo animale domestico seguendo le raccomandazioni nutrizionali fornite dal veterinario. Idealmente, sarebbe meglio se nutrissi il tuo cane in base alla sua taglia, razza, stile di vita, età e attività fisica. Prova a optare per alimenti biologici per il tuo cane. Se il tuo cane è allergico a qualsiasi alimento come mais, manzo, latticini o pollame, evita di acquistare quei tipi di alimenti per animali domestici che possono scatenare allergie. Assicurati di dargli dolcetti sani invece di condividere i tuoi pasti con lui come ricompensa.

 

Non saltare i controlli veterinari regolari

Il tuo veterinario locale può fornirti tutte le informazioni necessarie in merito alla vaccinazione e alla sverminazione del tuo cane. Assicurati di avere sempre con te una o due copie del libretto di vaccinazione del tuo cane, specialmente quando viaggi in una nuova città o paese con il tuo animale domestico. Salva il numero del tuo veterinario nel telefono per contattarlo nel caso in cui il tuo cane non si senta bene.

Mantieni il tuo animale domestico fisicamente attivo e stimolato mentalmente

Assicurati di trascorrere del tempo di qualità con il tuo animale domestico per mantenere la sua mente fresca e stimolata. Puoi svolgere attività divertenti con il tuo animale domestico, come fare una passeggiata veloce o preparare i suoi dolcetti fatti in casa preferiti. Assicurati di pulire le sue zampe dopo essere tornato a casa da una passeggiata. Inoltre, evita di avvicinarti al tuo cane se non ti senti bene e soffri di sintomi influenzali o febbrili. Puoi chiedere a chiunque nella tua famiglia o al tuo vicino di nutrire il tuo cane per te. Quando trascorri del tempo di qualità con il tuo cane, capisci le simpatie, le antipatie, i modelli comportamentali del tuo animale domestico, ecc.

Prenditi cura della cura e dell'igiene del tuo animale domestico

L'igiene orale è una parte vitale della cura degli animali domestici. Molti cani hanno gengive deboli e se non viene mantenuta una corretta salute orale, può causare infezioni alla bocca o perdita dei denti. Le unghie lunghe e troppo cresciute possono rendere difficile per i cani anziani camminare correttamente. Inoltre, le unghie lunghe tendono ad essere deboli e possono rompersi rapidamente, il che può essere molto doloroso.

Per riassumere

Durante questi periodi di stress, in cui le persone sono confinate nelle loro case a causa dell'epidemia di corona, è necessario prestare particolare attenzione alla forma fisica del proprio animale domestico. Molti proprietari di animali domestici evitano di portare i loro cani nei parchi pubblici e preferiscono rimanere in casa per evitare di essere infettati dal coronavirus. Pertanto, per mantenere il tuo animale domestico fisicamente in forma e attivo, puoi lasciarlo giocare nel prato o nel cortile di casa tua.

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I migliori sarm ammassanti

Each of Selective Androgen Receptor Modulators (SARMs) has unique properties. Here we’ll discuss most popular ones and their benefits:

Ostarine (MK-2866) optimal for novices

Ostarine is an incredibly dynamic SARM which can prevent loss of muscles. It is good for those who suffer from lack of calories during drying cycles, as they can burn fat without reduction of muscle mass.

Due to its properties, ostarine is often used in medical practice for treatment of muscle loss in patients. However, athletes mainly use it for boosting strength and stamina and for prevention of muscle loss.

Usually ostarine cycle lasts for 8 weeks. The dose varies from 10 mg to 25 mg, and it’s better not to exceed it since it may suppress HPTA.

Radarine (RAD-140) – possibly one of the most powerful SARMs

Radarin, aka RAD-140, is rather new drug, but it gained popularity for fast results with low sides. It is mainly used for increasing muscle mass and strength, and is suitable for cutting and bulking cycles.

It can provide huge increase in strength, which can help you to overcome yourself. It also boosts energy thus you can do workouts for much longer.

Ligandrol (LDD-4033) – perfect for bulking

Ligandrol is mostly taken for bulking and is preferred for its long half-life, which is about 1-1,5 days, therefore you can take it only once a day. It is also famous for low sides and as a powerful fat burner.

 

Cardarin (GW501516) perfect for cutting

 

Cardarine is used for increasing endurance and as a fat burner. It also reduces bad cholesterol in the blood. In medicine it is used to protect cerebral blood vessels from damage and stress, as well as to fight obesity.

 

Best SARM cycles for Cutting

MK-2866 Ostarine 20 mg / day along with Cardarine 10 mg / day for 2.5 months. This combo is perfect for keeping muscle mass, fat-burning, and endurance.

MK-2866 Ostarine 20 mg / day along with LGD-4033 Ligandrol 10 mg / day for two months. This combo can help you to increase muscle volume and to avoid of muscle loss.

SARM cycles for bulking

LGD-4033 Ligandrol 10 mg / day along with RAD140 10 mg for 2 months cycle. It provides fast bulking, with very low sides.

S23 10 mg, RAD-140 10 mg and Ibutamoren 20 mg / daily for an 2 months cycle. It can help you to gain mass extremely fast. Ibutamoren also boosts Growth Hormone levels which has additional benfits.

Best SARM cycles for cutting

LGD-4033 Ligandrol 10 mg in combo with GW501516 cardarin 10 mg daily for an 2 months cycle. This combo is powerful fatburner and also reduces water retention, besides it lowers bad cholesterol in the body.

Best SARM cycles for strength

RAD140 – 10 mg and S23 at 10 mg / day for 2 months cycle. This combo is perfect for muscle gaining and can be incredibly beneficial for power and strength.

YK-11 10 mg and LGD-4033 10 mg for 2 months. This combo is exceptional for increasing pure strength and muscle mass with low sides.

 

In order these SARMs to work effectively, one should train properly and combine the cycles with healthy habits and lifestyles. Also do not forget to eat proteins every day, especially after workout.

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Bodybuilding anastrozolo

Anastrozole is an aromatase inhibitor. In simple terms, it blocks functioning of aromatase enzyme, which is responsible for converting testosterone to estradiol. The drug is used during cycle with aromatizable anabolic steroids to reduce the negative effects of estrogen on the body.

Initially we should discuss the positive and negative effects of estrogen on the male body. Estrogens play an important role in various functions of the male and female body. The general health of the athlete and his results depend on these very functions.

Positive Effects of Estrogens:

  • play an important role in the immune system;
  • necessary in the nutrition of bone tissue;
  • have a positive effect on cholesterol levels;
  • necessary for the production of growth hormone (GH) and insulin-like growth factor (IGF);
  • play an important role in maintaining the “fluid balance” in the body at the proper level;
  • help to absorb glucose;
  • support sex drive.

Negative aspects of increased estrogen levels:

  • retain fluid in the body, swelling;
  • fatigue and increased muscle blockage during training;
  • acne that has not been previously observed;
  • the risk of prostate cancer increases;
  • blood clotting increases;
  • the risk of cardiovascular disease increases;
  • the risk of hypertension (high blood pressure) increases;
  • the risk of stroke increases;
  • cause gynecomastia (swelling and itching in the nipple area, breast enlargement);
  • decreased sexual desire;
  • female obesity;
  • extra sweating;
  • possible sleep disturbances;
  • can provoke hair loss;
  • possible disturbances in the work of the gastrointestinal tract.

 

With the help of aromatase inhibitors, the level of estrogens is controlled. The competent use of anastrozole allows not only to counteract aromatization, but also to simultaneously increase the level of free testosterone. If you follow the dosage regimen, the agent will be perfectly tolerated by the body, without any negative effects.

The drug Anastrozole was invented at the end of the last century, its original purpose – the treatment of breast cancer. The effectiveness of the drug in this area has been proven, this contributed to its popularity in sports when using anabolic steroids by athletes.

Anastrozole in bodybuilding is used when the athlete begins to use anabolic steroids, which prone to aromatization, such as testosterone and danabol. This steroids may cause gynecomastia. In simple terms, this is the growth of the mammary gland. That is why many athletes take anastrozole during steroid cycles.

It suppresses the enzyme, interfering with the destruction of testosterone and the production of estrogen. The main effect of anastrozole is:

  • prevention of fluid retention;
  • suppression of the production of female hormones;
  • stimulation of natural testosterone production;
  • prevention of testicular atrophy;
  • increased libido in men;
  • prevention of gynecomastia;
  • improving muscle tone;
  • an increase in the level of anabolic hormones in the blood;
  • prevention of hypertension.

To avoid serious side effects on the testosterone and danabol cycle, anastrozole should be used immediately. It is easier to prevent the development of serious diseases than to cure them.

Possible side effects of anastrozole

Any medicine has both positive effect and negative one. Problems can arise if the athlete exceeds the recommended dose or takes the drug for too long. For the normal functioning of the male body, estrogens are necessary. If you take anastrozole for a long time and uncontrollably on the cycle of anabolic steroids, the level of this hormone can reach critically low levels.

This can cause a number of side effects:

  • memory impairment,
  • apathy, drowsiness,
  • fatigue;
  • frequent mood swings up to depression;
  • violation of oxygen metabolism in tissues;
  • deterioration of blood clotting;
  • violation of the functionality of nerve cells;
  •  joint pain;
  • decreased bone strength (osteoporosis);
  • headache, dizziness;
  • decreased libido;
  • low sperm motility;
  • increase in blood cholesterol levels;
  • anemia, thromboembolism, thrombophlebitis;
  • skin rashes and itching;
  • thinning hair, baldness;
  • lack of appetite while gaining weight;
  • liver disease.

All this suggests that anastrozole in bodybuilding should be used with caution, blood counts should be monitored, and the recommendations of professionals should be followed.

How to use anastrozole on the cycle of anabolic steroids?

If you don’t use aromatizable steroids, then you probably won’t need the drug. And if you do steroid cycle with testosterone, then you cannot do without anastrozole.

It can be used even before the cycle of anabolic steroids in case your level of aromatization is increased, as can be seen from the analyzes. You do not need to take this drug at random. Anastrozole is also used during PCT to reduce the level of aromatization, if this occurs and is monitored by tests for Estradiol.

Anastrozole can be taken at any time of the day, but the maximum effect can be achieved when taken on an empty stomach. If you drink a medicine with plenty of water, it will be absorbed faster and penetrate into the bloodstream. When using testosterone, anastrozole is taken both on different days and every day, it all depends on your level of aromatization, which proceeds differently for everyone due to individual characteristics, as well as depending on the dosage of testosterone and its ester.

You should take Anastrozole during the whole period of steroid action. For example, when using testosterone propionate, anastrozole must be taken up to the fifth day after the last injection. And after long estered testosterones (enanthate, decanoate, cypionate, sustanon, etc.), anastrozole has to be taken for the third week after the last injection, and sometimes longer.

If you take steroids with a short half-life (methandrostenolone), then start taking anastrozole with a lower dosage and frequency (0.5 mg three times a week or every other day). After 15-20 days of administration, the blood test should be repeated.

When using testosterone propionate, for example, 100 mg. / every other day, the dosage of anastrozole can be 0.5 mg every other day, or every day 0.5 mg, or 1 mg every day, and the last intake of anastrozole should be on the fifth day after the last injections.

If you are using long-ester steroids, then start taking anastrozole few days after the first injection, and after two to three weeks check with the aim of adjusting the dosage, and the subsequent recheck should be done at least once a month.

It is important to carefully monitor your body in order to timely determine the imbalances in the hormonal background and timely prevent the occurrence of side effects, changing the frequency of taking accompanying drugs, up to their cancellation.

 

During post-cycle therapy, anastrozole is not used if the level of aromatization is not rises above the permissible values. It is not permissible to replace anastrozole with tamoxifen, since they have mutually exclusive effect.

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Insulina del bodybuilder

Insulin in bodybuilding

Why is insulin needed and how does it work?

Insulin is a peptide hormone, formed in the beta cells of the islets of Langerhans of the pancreas. It has a multifaceted effect on metabolism in almost all tissues. The main action of insulin is to lower the concentration of glucose in the blood. In bodybuilding, insulin is used due to its pronounced anabolic effect.

Insulin increases the permeability of plasma membranes for glucose, activates key glycolysis enzymes, stimulates the formation of glycogen from glucose in the liver and muscles, and enhances the synthesis of fats and proteins. In addition, insulin inhibits the activity of enzymes that break down glycogen and fats. That is, in addition to the anabolic effect, insulin also has an anti-catabolic effect.

The transport of glucose in two types of tissues depends to the greatest extent on insulin: muscle tissue and adipose tissue – this is the so-called. insulin-dependent tissues.

Insulin effects

  • increased absorption of glucose and other substances by cells;
  • activation of key glycolysis enzymes;
  • an increase in the intensity of glycogen synthesis – insulin accelerates the storage of glucose by liver and muscle cells by polymerizing it into glycogen;
  • a decrease in the intensity of gluconeogenesis – the formation of glucose in the liver from various substances of a non-carbohydrate nature (proteins and fats) decreases.

Anabolic action of insulin

  • enhances the absorption of amino acids by cells (especially leucine and valine);
  • enhances the transport of potassium ions into the cell, as well as magnesium and phosphate;
  • enhances DNA replication and protein biosynthesis;
  • enhances the synthesis of fatty acids and their subsequent esterification – in adipose tissue and in the liver, insulin promotes the conversion of glucose into triglycerides; with a lack of insulin, the opposite occurs – the mobilization of fats.

Insulin anti-catabolic action

  • inhibits protein hydrolysis – reduces protein degradation;
  • reduces lipolysis – reduces the flow of fatty acids into the blood.

The Dangers of Using Insulin

Perhaps the main factor in insulin’s bad reputation is the risk of hypoglycemia. On any forum, you can find messages of a warning nature, as if even a slight excess of the dose of insulin could be fatal. However, scientific and practical evidence suggests otherwise: the lowest lethal dose of insulin is 100 U, that is, a full insulin syringe. Many people survive even after 3000 IU doses! But in the event of a serious insulin overdose, there is no time to call an ambulance in a clear consciousness. Depending on the degree of overdose, it takes from several minutes to several hours to the development of a coma, so even lethal doses of insulin do not cause death if the timely flow of glucose into the blood begins.

What insulin is used in bodybuilding

In bodybuilding, short-acting and ultra-short-acting insulin should be used:

Short-acting insulin

Short insulin begins to act when injected subcutaneously after 30 minutes (therefore, it is administered 30-40 minutes before meals), the peak of action occurs after 2 hours, disappears from the body after 5-6 hours.

The best choice:

  • Humulin Regular
  • Actrapid HM

Ultra-short-acting insulin

Ultra-short insulin begins to act in 0-15 minutes, peak in 2 hours, disappear from the body in 3-4 hours. It is more physiological and can be administered immediately before a meal (5-10 minutes) or immediately after a meal.

The best choice:

  • Insulin aspart (NovoRapid Penfill, NovoRapid FlexPen).
  • Insulin lispro (Humalog)
  • Insulin glulisine (Apidra) are all semi-synthetic analogs of human insulin.

Advantages and Disadvantages of Insulin

Benefits:

  • Low cost of the cycle
  • Availability – the drug can be purchased freely at the pharmacy
  • High quality – counterfeits are practically excluded, unlike steroids
  • Lack of toxicity, low frequency of side effects, almost complete absence of the consequences of the course
  • Pronounced anabolic effect
  • Can be combined with anabolic steroids and other drugs
  • Lack of androgenic effects
  • Insulin DOES NOT have a toxic effect on the liver or kidneys, and also DOES NOT CAUSE sexual dysfunction.

Disadvantages:

  • Complex reception scheme
  • Significant fat gain
  • Hypoglycemia

Effetti collaterali

Hypoglycemia or a decrease in the concentration of glucose in the blood, which entails all other manifestations. Hypoglycemia can be easily prevented, read about it in the main article – Hypoglycemia.

Itching in the area of ​​the injection

Allergy – extremely rare

Decreased endogenous insulin secretion – occurs only with very long courses with high doses of insulin

A decrease in endogenous insulin secretion occurs only during exogenous use of insulin (duration of action of short-acting or ultra-short-acting insulin). Insulin, unlike other endocrine hormones, is not regulated by the hypothalamic-pituitary system and does not have a feedback principle. The only stimulators of insulin synthesis are the level of glycemia and food intake (through the mechanism of the secretin cascade). Therefore, even a very long-term use of insulin does not change its secretion, after its withdrawal. But this is not a positive quality of the use of this hormone, since the risk of developing hypoglycemic conditions is very high !! To stop hypoglycemia, it is necessary to use fast carbohydrates, and since short or ultrashort insulin is used, all fast carbohydrates entering the bloodstream are carried away in the process of lipogenesis in adipose tissue. Excessive use of insulin, its “overdose” leads to an increase in fat reserves. As an anabolic hormone, it is weak, but hypoglycemia leads to the release of growth hormone, which has an anabolic effect.

 

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cos'è il sustanon

Sustanon – testosterone mix

Testosterone is need for the successful functioning of hormonal levels, metabolic processes and the immune system in men. Low testosterone levels negatively affect sexual activity, reduce muscle mass, and contribute to the development of depression.

The initial goal of Sustanon was correction of testosterone levels in men, therefore it was included into the list of drugs used for hormone replacement therapy. But over time, athletes and professional bodybuilders drew attention to its properties. It has been used successfully as an anabolic steroid since the 1970s. Today, many athletes decide to buy Sustanon 250, for whom it is important to increase body weight without negative consequences for the body.

 

Structure

Sustanon 250 consists of four testosterone esters: propionate, phenylpropionate, isocapronate, decanoate. The composition also includes auxiliary substances: peanut oil as a solvent and benzyl alcohol as an antiseptic. All four forms of testosterone in the composition of the drug have their own period of action, which increases the effectiveness of the drug.

Sustanon properties and benefits

The high effectiveness and prolonged action of Sustanon makes frequent use unnecessary. Even one injection already provides a positive result. With a rare intake schedule, it is possible to maintain testosterone at the required level.

 

The main advantages of the product include:

  • ensuring the optimal level of hormone concentration;
  • a rapid increase in muscle mass;
  • improved metabolism;
  • activation of blood circulation processes;
  • anticatobolic effect by reducing the level of cortisol in the blood;
  • increase in the number of red blood cells in the blood;
  • increased sexual activity.

 

Contraindications and side effects

Testosterone injections should not be given for established or suspected prostate cancer. Sustanon 250 should be taken with caution by persons with epilepsy, heart failure, arterial hypertension, since prolonged use can cause complications. But in most cases, side effects occur against the background of improper intake of the drug or a significant excess of the permissible dosage.

 

Among the negative consequences should be highlighted:

  • female type fat accumulation;
  • increased blood cholesterol levels;
  • excessive hair loss, baldness;
  • acne;
  • painful sensations at the injection site;
  • increased blood pressure;
  • insomnia, depressed mood, unreasonable aggressiveness.
  • In rare cases, symptoms of gynecomastia in men and prostate hypertrophy are possible.

Taking the drug by women can cause menstrual irregularities, coarsening of the voice, deterioration of ovarian activity.

 

How to take Sustanon correctly

Correct intake of the drug allows you to reduce the risk of side effects to a minimum. Start with a weekly injection at a dosage of 250 mg / week intramuscularly. Injections are best done in the buttocks area. In the future, the dosage is increased and brought to 1000 mg / week. The maximum duration of cycle is 10 weeks. The duration of action is 5-6 days.

Interaction with other steroids

The injections of the product can be taken both solo and in combination with other drugs. The combination with nandrolone promotes the growth of muscle fibers, and the combination with Winstrol has a positive effect on drying. Combinations with such drugs as Turinabol, Boldenone and others are also possible.

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Dosaggio di Arimidex durante il ciclo

Arimidex (Anastrozole) is an aromatase inhibitor, an enzyme that converts testosterone to estradiol. When used with anabolic drugs, Anastrazole minimizes the side effects of estrogen.

Anastrazole controls the level of this female sex hormone, it also increases the levels of free testosterone. The drug is safe and well tolerated when correct doses are used.

  • Reduces estrogen levels
  • Increases the effectiveness of steroid hormones.
  • Promotes natural testosterone synthesis even with androgen steroids.
  • Prevents gynecomastia in men.

Pharmacodynamics

The non-steroidal active ingredient selectively blocks aromatase. In postmenopausal women, folliculin, androstenedione and aromatase promote estradiol synthesis.

With a decrease in the estradiol level, breast cancer is treated. The estradiol level is reduced by 80%. The drug has no progestogenic, estro or androgenic activity.

When the tablets are taken orally, the active substance is rapidly absorbed from the gastrointestinal tract. Its binding to plasma proteins will be 40%. Accumulation in the body does not occur. The maximum concentration in the blood will reach after 2 hours if the agent is taken on an empty stomach.

Dealkylation, hydroxylation, glucuronidation ensure the absorption of the drug by the liver. Urine and blood contain the main metabolic product, triazole. Excretion of drug metabolites is 3 days.

Benefits and harm

  • Anastrozole removes unnecessary fluid from the body.
  • It has a positive effect on blood cholesterol profile.
  • Increases libido in men.
  • Prevents arterial hypertension.
  • Decreases estrogen dependent inhibition of the pituitary-hypothalamus-testicles axis.
  • The remedy is popular for PCT during the recovery period.
  • The medicine helps well with hormone replacement therapy.

One should remember that estradiol is needed by the body for normal functioning. Therefore, it is important for an athlete to remember about biological role of estradiol and to keep it on the proper level.

 

The low estrogen levels may cause

  • Memory impairment
  • Mood changes
  • The problems with joints
  • Depression.
  • Decreased Libido.
  • The cholesterol level will rise.

 

How to take it right

The tablets are indicated for bodybuilders with experience after a cycle of anabolic steroids at maximum dosages. The medicine is used in two cases: before the cycle of anabolic steroids for prophylaxis with therapeutic doses, and after the cycle, to prevent the side effects of steroids.

The tablets should be taken on an empty stomach with a large volume of water. In this case, the active ingredient will quickly enter the bloodstream from the digestive system.

On the cycle, Anastrozole should be taken every other day during 2 weeks. The optimal dosage for good athletic performance does not exceed 250 mcg once every 2 days.  To reduce the estardiol level by half, a dose of 0.5-1 mg is recommended. For preventive measures in bodybuilding, 0.5 mg is enough every other day.

For gynecomastia 1 mg is used until the symptoms are eliminated, then 0.5 mg every other day. It is important to remember that not all anabolic steroids are aromatized. For example, in Anadrol, the transformation into estrogens is insignificant.

When using anabolic steroids with a short half-life, like Methandrostenolone, after 10 days, an analysis is made for the concentration of estradiol in the blood, Anastrozole is taken at 0.5 mg every other day. Then, after 10 days, estradiol is examined, the dose is adjusted.

When using anabolic steroids with long esters, for example, Sustanon, the dosage is 0.5 mg every other day. It is required to make a test for estradiol in 3 or 4 weeks after beginning of a cycle. The control analysis is carried out approximately in 10 or 14 days after you start taking Anastrozole. You should decrease the dosage if side effects are observed.

You should not combine Tamoxifen with Anastrozole. With such drug interactions, there is a mutual weakening of these drugs. It is forbidden to consume alcohol with Anastrozole, otherwise, with such compatibility, the pharmacological effect of the drug will not appear, undesirable consequences will appear.

 

Terapia post ciclo

It is important to remember that drugs that inhibit aromatase are not used in post-cycle therapy, they are used during the cycle and after the use of anabolic steroids (before PCT).

 

During PCT, drugs that block estrogen receptors (Clomid, Tamoxifen) are taken after a cycle for 2-3 weeks. Tamoxifen requires 10-20 mg per day, or Clomid 25-50 mg per day is used. The dose is gradually reduced towards the last week.

 

Thanks to chorionic gonadotropin, testicular atrophy can be prevented. It is used for heavy cycles, the duration of which is more than 6 weeks. It is introduced on the last 4-5 weeks of the cycle and should be used until discontinuation of steroids. Then you need to switch to drugs that block estrogen receptors.

 

The use of Cabergloline is recommended during cycles with progestin drugs, due to which the prolactin level increases. The dosage is 0.25 mg every 4 days for the entire cycle.