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Andriol / Testosterone Undecanoate / Restandol profile: usage and stacks

Les culturistes utilisent non seulement des esters de testostérone injectables, mais aussi un esters oraux (éthers) - ce sont  undécanoate de testostérone connu sous les noms de marque  andriol, restandol, etc. and méthyltestostérone. But now let’s talk about andriol.

This is very special drug with it’s unique advantages and disadvantages. Professional bodybuilders usually use it only in the pause between cycles but amateur bodybuilders, females and athletes too concerned with safe usage can use it in separate cycles.  Testosterone undecanoate is being converted in the body into dihydrotestosterone, which almost does not aromatize, therefore estrogen-related side effects are not an issue.

Andriol is taken orally, therefore, on the first glance, it cannot bypass the liver where all oral testosterones are being destroyed. However, pharmacologists invented following solution: testosterone undecanoate (Andriol) is being made in capsules, which contain very specific fatty acid, which makes andriol bypassing the liver and reach it’s target through lymphatic system. Unfortunately, it did not work out as planned completely. Part of substance is being absorbed through lymphatic system and converted to test as planned. Another part is moved out of the body faster than it become effective. The good thing is that the liver is not affected.

Average dosage is 6 capsules a day (and this is 240 mg/ ED); however, only 6.83% of substance actually  reach bloodstream, the rest is wasted. Furthermore, it is being moved out of the body very quickly through the kidneys. Try to imagine what happened if you inject let’s say regular testosterone suspension at a dosage 240 mg/ED (1700 mg/week)! But with andriol dosages below 240 mg/ED have very low effect, even 6 caps/day produces relatively moderate effect.

Ainsi l'andriol est inutile pour les bodybuilders «sérieux» sur des cycles lourds et principalement utilisé pour améliorer la libido pendant la PCT (thérapie post-cycle) pour maintenir le niveau de test.

However, it has it’s own unique niches! Because of low testosterone release it is extremely safe and could be used by cautious athletes and females. Furthermore, it is not detectable just in one week after cycle is over thus making it a good drug when contest is coming close.

L'avantage supplémentaire d'Andriol est qu'il n'affecte pas la production naturelle de testostérone à moins d'être pris trop longtemps et à des doses élevées.
Dosage et utilisation

La posologie quotidienne régulière de l'undécanoate de testostérone varie de 240 mg (6 capsules) à 480 mg (12 capsules) répartis en trois parties avec un intervalle de temps égal. Boire avec de l'eau après le repas. Ne mâchez pas.
Empilement

When used between cycles, it is good idea to combine andriol with oxandrolone (anavar). This will help to maintain testosterone level and thus libido and prevent muscle loss. Also Andriol /  anavar combo could be used as a safe standalone cycle: 240 mg of andriol / ED  plus 30-40 mg anavar / ED with possible addition of primobolan (400-600 mg/week) for ten-twelwe weeks. This is very safe combination. PCT is needed only if  included. Athletes over forty can find this very effective and safe, too.

Une autre pile est l'andriol 240 mg / semaine + anavar 20 mg / ED + déca 200 mg / semaine pendant 10 à 12 semaines. Certains PCT (tamoxifène, clomid) sont nécessaires. Un cycle plus court est possible si plus de déca est utilisé (400 mg / ED).

De plus, dans certains cas, l'andriol pourrait être associé au propionate de testostérone - c'est pour les personnes qui souhaitent réduire le volume des injections. Mais à notre avis, c'est un gaspillage d'argent.

Andriol convient également aux cycles pré-compétition.

Effet secondaire et PCT

Andriol est l'éther de testostérone et les effets secondaires liés aux androgènes pourraient être un problème en théorie. Cependant, en raison de leur faible action, ces effets sont si faibles que l'andriol pourrait être considéré comme un médicament très sûr à moins que la dose ne soit trop élevée. Seules les doses supérieures à 400-500 mg commencent à montrer tous les effets secondaires courants de la testostérone et affectent la production d'hormones naturelles.

Aucun PCT (thérapie post-cycle) n'est nécessaire en dessous de 400 mg / semaine.

Temps de détection

Il est détectable par des tests de dopage une semaine seulement après utilisation.
Usage féminin

Andriol (undécanoate de testostérone) est le seul médicament qui pourrait être utilisé par les femmes sans aucun danger. La posologie quotidienne est de 120 à 240 mg. En outre, il se combine bien avec anavar (oxandrolone) et parfois, primobolan.

Par exemple, une athlète féminine peut faire 120 mg d'andriol / ED et 50 mg de / semaine pendant quatre à six semaines, puis faire une pause de trois semaines et continuer avec 50 mg / semaine avec du winstrol (stanozolol) 10 mg / ED pendant 4 autres. -6 semaines. Un PCT modéré est recommandé.

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L-thyroxine (Levothyroxine Sodium, T4)

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T4 is pro-hormone, which your body converts into T3 at necessary rate only and thus it could be considered as much milder and safer drug than T3.

Levothyroxine sodium is an excellent fat burner since your metabolism is greatly increased while being on it. You can afford to be a little sloppier on pre-contest dieting since it will still burn fat when you are taking in a lot of calories since your metabolism is going haywire. It’s biological activity is 4-5 times less than liothyronine T3 if comparing mg to mg, however, hormonal levels remain more stable and price is also much lower. And there are some other unique advantages, which makes it very competitive with T3 such as appetite suppression, less need of sleep and increasing of physical durability (stamina), so question “which one is better” depends on your goals.Clinical pharmacology book by Goodman says: “Liothyronine is less desirable for chronic replacement therapy due to the requirement for more frequent dosing (plasma t1/2 = 0.75 days), higher cost, and transient elevations of serum T3 concentrations above the normal range. In addition, organs that express the type 2 deiodinase use the locally generated T3 in addition to plasma T3, and hence there is theoretical concern that these organs will not maintain physiological intracellular T3 levels in the absence of plasma T4”

Levothyroxine is widely used by bodybuilders and fitness addicts on pre-competition cycle in order to get relief, also used by overweighed people to reduce weight. It increases metabolism and produces general stimulating effects. However, this substance should be used wisely.

t4 dosage bodybuilding

It is recommended that levothyroxine be taken with an empty stomach approximately half an hour to an hour before meals to maximize its absorption. It is also recommended that the patient take the tablet with one glass of water to ease swallowing as well as to help the tablet dissolve for absorption. Dosages vary according the age groups and the individual condition of the patient, body weight and compliance to the medication and diet. Maximum dosage may reach 400 mcg per day but that is rare. Monitoring of the patients condition and adjustment of the dosage is periodical and necessaryMost people need to be careful to start with a low dosage, about 25 mcgs. per day and increase by about one tab of 25 mcgs every 3-5 days.

On days that you take multiple tabs, divide the tabs evenly across the day (i.e. 100 mcgs. would be 4 doses of 25 mcgs. spread evenly across the day.) Don’t take for more than 5-7 weeks at a time to keep the thyroid functioning properly. After doing a cycle of this drug, make sure you go 4 weeks (better 8 weeks or more) before doing it again as to allow normal thyroid functioning to return.

 

Cycle 1: classic

Start with 25 mcg / day of T4 and increase by 25.

Do 25 mgs of Metoprolol at the morning (this is beta-blockader, which eliminates heart overload and heartbeating). If heart rate at the afternoon is more than 70 beats/min, take 25 mgs more.

Increase daily dosage of T4 to 150-300 mcg / ED split on 3-4 equal parts. The last one should be consumed before 6 p.m. At high dosages you can increase Metapronol to 100 mg / ED (two times by 50 mg), but in fact metapronol dosage should be found  individually keeping heart rate between 60 to 70 beats / min. If heart rate is more than 80 – increase metaprolol by 25 mg, if below 60 – decrease by 25 mg.

Watch your blood pressure, it should not be higher than 140/100 mm Hg. Art. Metoprolol reduces blood pressure, too.

Length of treatment should be 4-7 weeks. Do not quit suddenly, smoothly decrease T4 dosage starting 2 weeks before the end of cycle, this will help to restart your thyroid.

In case of diarrhea – use loperamid.

Minimal gap between cycles – 4 weeks

 

Cycle 2: clenbuterol + L-thyroxin (T4) + yohimbine

When taken with clenbutérol, this is the single best fat-burning combination that is available today (with the possible exception of DNP). It also helps to make steroids more effective since it is such a good aid for protein synthesis.

This powerful combo is used in some ready-made fat-burners, however, you can save a lot of money if acquire every of these substances separately. High effectiveness of the cycle is supported by the ability of T4 (or T3) not only increase metabolism and launch fat-burn) but also increase response of the receptors responsible for clenbuterol and yohimbine.

Let’s consider ONE UNIT of this stack like following:

Clenbuterol – 40 mcg +
L-Thyroxine – 25 mcg +
Youhimbine – 5 mg (you can acquire it in sport nutrition shops. If you can’t find it – just disregard)

Recommended cycle:

Day 1-3: 1 unit
Day 4-6: 1,5 units
Day 7-9: 1 unit at the morning and 1 unit afternoon
Day 10-12: 1,5 unit
Day 13-15: 1 unit
Day 16-19: 0,5 units.
Day 20-21: 0, 25 units

Take 30 mins before breakfast with water.

After the cycle make 3 weeks rest before the new one.

In case of fever use 1-2 mg of ketotifin afternoon. For heart protection do beta-blockaders like metaprolol 100 mg split on two times/day

 

Tricky ways of usage Levothyroxine T4

Human body produces 90-110 mcg of l-thyroxine daily. For fat-burn it does not make sense to take just replacement dosages because your thyroid simply decreases production in response and you’ll come to what you started with – the same T3/T4 levels in your body. Thus you have to consume dosages, which are higher than natural. But it’s possible to cheat the gland. If you take 12-25 mcg once every three days it will not affect endogenous T4 production thus making aggregated level higher (!)

I.e. in order to encourage metabolism, optimal dosage is not replacement dosage, but a dosage, which can increase general hormone levels without affecting endogenous thyroid production! Replacement dosage may help only to the people with low thyroid production, but why take more risking toxic effects while you can use much lower dosages?

For instance, normal production is 100 mcg/daily. Patient has 80 mcg/ daily. If he takes 100 mcg / daily he’ll get back to normal, but natural thyroid production will be shut down. However, if he does 25mcg every three days, his body will still produce this very same 80 mcg thus making around 90 mcg in total. Got the idea? Anyway you should discuss this with your GP. For bodybuilding you can use the same scheme – either toy with high dosages or make just minor “tuning” with 25 mcg every three days.

This is safe way of usage, but, of course, effect is incomparable to 150-300 mcg/day. It’s advisable only for relatively small fat-burn.

 

Medical usage of T4

This medicine is a hormone replacement usually given to patients with thyroid problems, specifically, hypothyroidism. It is also given to people who have goiter or an enlarged thyroid gland.

Precautions and side effects

There are also foods and other substances that can interfere with absorption of thyroxine replacement. Avoid taking calcium and iron supplements within 4 hours of the medication and avoid taking soy products within 3 hours of the medication as these can reduce absorption of the medication. Other substances that reduce absorption are aluminium and magnesium containing antacids, simethicone or sucralfate, Cholestyramine, colestipol, Kayexalate. Other substances cause other adverse effects that may be severe. Ketamine may cause hypertension and tachycardia and Tricyclic and tetracyclic antidepressants increase its toxicity.On the other hand Lithium causes hyperthyroidism by affecting iodine metabolism of the thyroid itself and thus inhibits Synthetic levothyroxine as well. Synthetic levothyroxine may have adverse side effects like: palpitations, nervousness, headache, difficulty sleeping, insomnia, swelling of the legs and ankles, weight loss and/or increased appetite. Allergies to the medicine are unlikely, but if the patient develops a severe reaction to this drug such as difficulty breathing, shortness of breath or swelling of the face and tongue it is imperative that the patient immediately seek medical attention. Acute overdose may cause fever, hypoglycemia, heart failure, coma and unrecognized adrenal insufficiency. Acute massive overdose may be life-threatening; treatment should be symptomatic and supportive. Massive overdose may be a require beta-blockers for increased sympathomimetic activity. The side effects of overdosing appear 6 hours to 11 days after ingestion.

Prolonged use of high dosages in theory may lead to serious problems with thyroid and suppression of endogenous hormone production (fortunately, studies shows only 20% down after 3 weeks of usage). However, when used properly at recommended dosages, thyroid function restores after 3-4 weeks

Levothyroxin has adrenalin-like effects including increased heart rate and nervousness, which could be avoided by using beta-blockaders

 

Advantages of T4

  • Extremely powerful fat-burner in combination with clenbuterol
  • Increased stamina
  • Lower sides comparing to T3
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Long R3 IGF-1 (Insulin-like Growth Factor)

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IGF-1 is the abbreviation for Insulin-Like Growth Factor 1. This is a naturally occurred long-chain polypeptide protein hormone and not a dangerous steroid. IGF-1 has molecular structure, which is quite similar to insulin. IGF-1 plays a vital role in childhood growth, especially bones and stimulates anabolic effects (muscle growth) in adults. IGF-1 greatly boosts muscle mass by inducing a state of muscle hyperplasia (increase in number of new muscle cells) in the body

Long R3 IGF-1 is a more potent version of IGF-1. It’s chemically altered to prevent deactivation by IGF-1 binding proteins in the bloodstream. This results in a longer half-life of 20-30 hours instead of 20 min.
There are 70 inter-connected amino acids that make up a single chain of IGF-1. This hormone is produced when the liver is stimulated by human growth hormone (HGH). When levels of HGH rise in the blood, the liver responds by producing more IGF-1. These higher “bursts” spur growth and regeneration by the body’s cells, especially in muscle cells. Increases in IGF-1 levels have shown positive effects on increases in muscle strength, size, and efficiency. When you do not have enough IGF-1 in your body, whether caused by disease, malnutrition or a hormone imbalance, your growth can be stunted.

Le but principal de l'IGF-1 est de stimuler la croissance cellulaire. Chaque cellule du corps humain peut être affectée par l'IGF-1, mais les cellules des muscles, du cartilage, des os, du foie, des reins, des tissus cutanés, des poumons et des nerfs ont tendance à être les plus affectées.

Products which increase IGF-1 can help improve muscularity and healing and recovery times. IGF-1 can also stimulate a decrease in body fat, an increase in lean muscle mass, improved skin tone and restful sleep. IGF-1 has also been documented to increase the rate and extent of muscle repair after injuries or strains. Not only do muscles recover more quickly, they also tend to return stronger and healthier than ever when levels of IGF-1 in the bloodstream are at their highest.

L'IGF-1 a également un effet positif sur le processus de vieillissement. Il peut prévenir la dégénérescence des muscles, des tissus cutanés et des os liée à l'âge. Parce que les niveaux d'IGF-1 ont tendance à se stabiliser et à chuter rapidement lorsque le foie n'est pas stimulé par la production de HGH, ces avantages sont plus importants lorsque des niveaux constamment élevés de HGH sont maintenus.

Combined with other supplements and monitored responsibly, IGF-1 can be beneficial for those individuals who suffer from stunted growth or growth hormone deficiencies as well as those individuals who strive to be in the best physical shape possible. Athletes, bodybuilders and physical competitors around the world are learning all about the benefits of IGF-1 and implementing the growth hormone into their daily regimented workouts. Whether you are an athlete yourself, or you prefer to workout more than a few times a week, IGF-1 can be beneficial for you. Even if you aren’t an athlete at all, but are looking to get as healthy and fit as possible for your own reasons, IGF-1 can be beneficial for you.

IGF-1 dosages and length of cycle

IGF-1 novices will be able to use a smaller dose than a more advanced user. For your first IGF-1 cycle, you need to remember that less is more, meaning that you don’t have to use a lot to get great results. This is not like testosterone where you need big doses for big muscles. For your first or second cycle with IGF-1, you will use 50mcg per injection day, 3 days per week (or 20-25 mcg daily), and split into two daily injections. For LONG R3 IGF-1 you can inject less frequent. for advanced users dosages may grow but never exceed 120 mcg daily.

The same is true for the length of cycle. IGF-1 effectiveness falls rapidly after prolonged use. Some users report 40 days, some 60 days, but our advice is to limit IGF-1 cycle for 4-5 weeks to get maximum effect then take rest. Some advanced users may do 50 days but only if they know what they’re doing. Too much IGF-1 will result in deregulation of IGF-1 receptors on the surface of muscle cells. This will jeopardize any gains from the injected IGF-1 since very little receptors means very little response! Time gap between cycles should be 20-40 days.

IGF-1 is also best taken either subcutaneously (preferably) or IM, having more direct effects on the body when injected. It’s also recommended to be taken during the morning/evening only (novice) or after work out only  (novice) or morning/evening plus after weight training sessions (advanced user). So advanced user makes from two to four injections daily.

Utilisation d'IGF-1

Assuming that we use the lyophilized form (dry powder) of Long R3 IGF-1, equivalent to a 1000 mcg vial, it is best prepared by using 1ml or 2ml of acetic acid. Let the acetic acid seep into the vile after removing the vacuum from the container. Then, let the mixture in the vial sit for a while. Put it in the fridge where the IGF-1 mixture can dissolve without accidentally knocking the vial or shaking its contents. Then afterwards, it’s all about diluting your Long R3 IGF-1 in NaCl or bacteriostatic water before intra-muscular or subcutaneous entry.

In most cases you have 1mg (1000mcg) bottle of substance, with 1 ml of pre-made acid. Since we want to use 25mcg for our injection, you need to use an insulin syringe (29 gauge 50 IU for easier measuring) and withdraw to the 2.5 tick mark on the syringe. Yes, that is a very, very small amount to withdraw which is why we recommend the 1/2cc or even 30 IU syringes. Now using acetic acid can be very painful, and it is almost impossible to inject such a small amount so you will now use bacteriostatic water or NaCL water to add more volume to the syringe. This will also help reduce the pain of the acid injection. After you withdraw your small 2.5 IU on the slin pin, just finish filling the syringe with the water.

But what to do if IGF-1 comes in powder and there’s no acid supplied (generic brands)?
That’s not easy subject to answer 🙁

If you dissolve in bacteriostatic water lifetime will be too short. Some users claim it’s just 2-3 days under +4C, so in this case you have to dissolve TOO small dosages, which is very difficult. However, in special acid solution it lives up to 4 weeks. Put 4 ml solution into 1 mg IGF-1. 1 mg = 1000mcg

How to prepare acid solution? You need bacteriostatic water, acetic acid, syringe 10 ml, and filter 0.22 mm or better 0.11mm

Take 1 ml 99% acetic acid then 7ml sterile water, shake well then leak out 7 ml out of total 8ml. Add 7ml of water AGAIN, so finally we receive 1,5% acetic acid solution.

Preferably put filter onto the syringe and put 4 ml of solution into 1mg IGF1 vial.

Insulin syringe has 40 IU for 1 ml (when measuring insulin and IGF). Thus 4 ml of solution contains 250 mcg per ml.

1000mcg/4mL: 31 mcg per 5 IU
40 IU = 250 mcg
20 IU = 125 mcg
10 IU = 62,5 mcg

So, if your dosage is 30 mcg utilize 5 IU, if dosage is 25 mcg, utilize ~4.5 IU

It’s not advisable to freeze liquid but if there’s no other way – do it no more than 1 time

Stacking IGF-1

The IGF-1 that’s produced from the use of fast acting Nandrolone ou Trenbolone is nothing significant when you compare to the amount that’s contained in a single 10mcg Long R3 injection. Having said that, it’s safe to inject exogenous IGF-1 while taking either one of these compounds.

IGF-1 and Human Growth Hormone?

Long R3 IGF-1 can directly stimulate muscle growth when compared to human growth hormone (HGH). This is because HGH indirectly results in growth and repair by first inducing IGF-1 release in the liver. If you don’t have to worry about IGF-1 release in the liver (because your directly injecting the IGF-1), new growth will be optimized.

Usage of IGF-1 brings more faster results than HGH because HGH acts indirectly and process is slower.

If stacking with HGH after workout you can do for example like this: 5 IU HGH then 50 mcg IGF after 20 minutes (or smaller dosages if you make more frequent injections).

Is there a benefit to using both of these substances together?

“Many research studies have shown that GH and IGF-1 act synergistically to augment the effect of either hormone taken individually. So, the greatest results will take place when effective dosages of both hormones are injected. Usually 10-20mcg of IGF-1 (post workout) and 4-8 IU HGH EOD (with breakfast and at 1 p.m.) is the ideal stack for optimal results and minimal side effects.

Medical usage

Tissue build up is one of the main features of IGF-1, so I’d say it’s of greater value. IGF-1 can genetically change muscular and cellular counts within the body; it can also enhance the body’s ability to regenerate damaged tissue. In fact, IGF-1 is now under intensive research for its potential to repair tissue in burn patients, and for its regenerative effects on AIDS patients suffering from muscular wasting. Immediate effects are, of course, impossible to observe since it takes a respectable amount of time to see any visible changes in muscular repair.

There’s no known lethal risk of administering IGF-1 to diabetic patients. In fact, IGF-1 can reduce the body’s need for insulin, and according to one short study, it can reduce insulin dependence of the body by as high as 45%. This may bring very promising results if we are allowed to study this matter further. If anyone experiences any uncomfortable side effects, stop it’s usage and see if the side effect disappear.

Side effects of IGF-1

IGF-1 is commonly known to cause feelings of fatigue. Some people feel very tired quickly when using this compound. It can, however, be looked at in a more positive light since more sleep means better growth. Other side effects include muscular stiffness, headaches, occasional nausea, and some also claim that it’s sometimes responsible for hypoglycemia or low blood sugar.

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Cytomel (liothyronine sodium, triiodtironine, T3)

Il existe trois hormones thyroïdiennes liées responsables du métabolisme - le tricodide-thyronine (L-T3), la L-thyroxine (L-T4) et l'hormone thyrotrophique responsables du lancement de la production de T4. La plupart du T3 naturel n'est pas produit directement par votre glande thyroïde, mais est plutôt converti à partir de l'hormone thyroïdienne T4. Cytomel est une liothyronine sodique (T3) fabriquée synthétiquement qui ressemble à l'hormone T3 naturelle.

Cytomel (Liothyronine Sodium, L-T3)  has proven to be 4-5 times more biologically active and to take effect more quickly than lévothyroxine T4. T3 has a faster onset of action as well as a shorter biological half-life, probably due to less plasma protein binding to thyroxine-binding globulin and transthyretin.

En médecine scolaire Cytomel (liothyronine sodique) est utilisé pour traiter l'insuffisance thyroïdienne (hypothyroïdie). Parmi les autres symptômes secondaires figurent l'obésité, les troubles métaboliques et la fatigue.

Le T3 n'est pas dangereux - il arrêtera temporairement votre fonction thyroïdienne naturelle, ce qui peut produire un décalage après la supplémentation à moins que vous ne diminuiez correctement - il mangera cependant du muscle, à moins que vous ne preniez anavar, winny ou primo tout en le prenant. C'est un super stack avec clen.
Cytomel T3 en musculation et fitness

Natural T3 is a regulator of the oxidative metabolism in cell’s mitochondria. Thus higher T3 level means  an increase in overall metabolic activity – your body spends more energy and burns more fat because of this. In low dosages, especially if taken along with steroids, it can even serve for certain muscle growth – due to increased metabolism. However, in high dosages it shifts towards catabolism and burns fat along with muscles.

Les culturistes profitent de ces caractéristiques et stimulent leur métabolisme en prenant Cytomel (liothyronine sodique), ce qui provoque une conversion plus rapide des glucides, des protéines et des graisses. Les culturistes, bien sûr, sont particulièrement intéressés par une lipolyse accrue, ce qui signifie une augmentation de la combustion des graisses. Les culturistes concurrents, en particulier, utilisent Cytomel (Liothyronine Sodium) pendant les semaines précédant un championnat, car il aide à maintenir une teneur en graisses extrêmement faible, sans nécessiter un régime alimentaire contre la faim. Les athlètes qui utilisent de faibles doses de Cytomel (Liothyronine Sodium) rapportent que par la prise simultanée de stéroïdes, les stéroïdes deviennent plus efficaces, probablement en raison de la conversion plus rapide des protéines.

Cytomel (Liothyronine Sodium), is a good replacement for proviron on pre-competition cycles, especally for females. The over stimulated thyroid burns calories like a blast furnace. Those who combine T3 and clenbuterol receive synergetic effect especially because of better regulation of beta 2 receptors in fat tissue, which clen tends to deregulate. As a result these two compounds burn an enormous amount of fat.

Une bonne alimentation riche en protéines est importante, il est souhaitable de prendre des stéroïdes non gonflants comme le winstrol ou le primo tout en prenant T3, sinon l'athlète risque de perdre trop de muscle, en particulier pendant un régime.

Une bonne pile pour des résultats maximaux pendant un temps minimal pourrait être l'insuline, T3, AAS comme primo ou winstrol et HGH.

 

Usage féminin

Cytomel (Liothyronine Sodium) est également populaire parmi les culturistes féminines. Étant donné que les femmes ont généralement un métabolisme plus lent que les hommes, il leur est extrêmement difficile d'obtenir la bonne forme pour une compétition compte tenu des normes actuelles. Une réduction drastique de la nourriture et des calories sous la barre des 1000 calories / jour peut souvent être évitée en prenant Cytomel (Liothyronine Sodium). Les femmes, sans aucun doute, sont plus sujettes aux effets secondaires que les hommes, mais s'entendent généralement bien avec 50 mcg / jour. Un apport à court terme de Cytomel (Liothyronine sodique) à une dose raisonnable est certainement plus sain qu'un régime alimentaire très faim.

 

Effets secondaires de Cytomel

La T3 augmente également la production d'hormone de croissance (HGH), ce qui n'est pas mauvais en soi, mais peut entraîner une brûlure musculaire encore plus importante avec la graisse car la HGH est également un composé fortement lipolytique, et c'est un autre mécanisme par lequel la T3 peut exercer ses effets. Dans le cas de la pile autonome T3 + HGH, cela peut être un problème, mais l'utilisation de certains stéroïdes anabolisants va vous aider.

Les effets secondaires possibles sont: tremblement des mains, nausées, maux de tête, transpiration élevée et augmentation du rythme cardiaque. Ces effets secondaires négatifs peuvent souvent être éliminés en réduisant temporairement la dose quotidienne.

 

Dosage et utilisation de Cytomel T3

En ce qui concerne la posologie, il faut être très prudent car Cytomel (Liothyronine Sodium) est une hormone thyroïdienne très puissante et très efficace. Il est extrêmement important que l'on commence avec une faible dose, en l'augmentant lentement et uniformément sur plusieurs jours. La plupart des athlètes commencent par prendre un comprimé de 25 mcg par jour et en augmentant cette posologie tous les trois à quatre jours d'un comprimé supplémentaire. Une dose supérieure à 100 mcg / jour n'est ni nécessaire ni recommandée. Il n'est pas recommandé que la dose quotidienne soit prise en une seule fois, mais décomposée en trois doses individuelles plus petites afin qu'elles deviennent plus efficaces.

Il est également important que Cytomel (Liothyronine Sodium) ne soit pas pris pendant plus de six ou huit semaines maximum. Au moins deux mois d'abstinence doivent suivre. Ceux qui prennent des doses élevées de Cytomel (Liothyronine sodique) pendant une longue période risquent de développer une insuffisance thyroïdienne chronique. En conséquence, l'athlète pourrait être obligé de prendre des médicaments contre la thyroïde pour le reste de sa vie.

There are some opinions that using cytomel is absolutely safe for a long time and it’s easy to restore thyroid production afterwards.

-I quote – The horror stories of people on permanent thyroid replacement just aren’t true. …people recovering their thyroid hormone relatively quickly (within months, at most) after going off of several YEARS (!) of thyroid replacement therapy. …we can safely spend an athletic career using Cytomel 9-10 months out of the year, and just taking those few months off to normalize ourselves. Is this aggressive? Yes. Is this unsafe? NO. – end of quote-

Maybe that’s true. But maybe not. So in this 50/50 situation we would advice to stay on “cowardly” side and use T3 with all precautions until the opposite will be scientifically proven.

Il est également important que la posologie soit réduite lentement et uniformément en prenant moins de comprimés et ne soit pas interrompue brusquement.

Ceux qui envisagent de prendre Cytomel (Liothyronine Sodium) devraient d'abord consulter un médecin afin de s'assurer qu'il n'y a pas d'hyperfonction thyroïdienne. Si vous n'avez jamais utilisé T3 auparavant, il est suggéré de réduire votre temps constant et d'augmenter votre période de montée en puissance pour déterminer votre réaction à t3 avant une utilisation intensive.

Some people wait until your thyroid shuts down in a cutting cycle (as it will when on DNP , heavy ECA , clen – anything that raises the body temp high), however, it should just be part of the whole cycle, not just replacement therapy on the end when you are on low endogenous T3.

When it’s used in a bulking cycle to help absorb all the protein – never go over 50mcg / ED, better even do 25mcg / ED. For cutting cycles dosage might be higher.

T4 peut également être utilisé à bon escient de la même manière, mais bien sûr les dosages sont différents - le rapport de t4: t3 est d'environ 4: 1 ou 4,5: 1 donc 100 mcg de t3 = environ 400-450 mcg de t4

Common approach is to increase T3 from zero to full dosage during the fists 4-7 days and then decrease at the same rate at the end. However, thyroid shuts down rather quickly, so, in order to restart the gland after the cycle it’s better to lengthen “decrease” period, for instance you spend 5% of time of increasing dosage then 40-50% of time on max throttle then remaining time on slow and even decrease of the dosage over the weeks. With this you may come to the end of cycle with warming up thyroid and smoothly finish using of tabs.

For instance, here’s an example of 3 weeks cycle and .25 tabs

4 jours = 1, 1,5, 2, 3 onglets
7 jours = 4 onglets
10 jours = 3, 3, 2, 2, 2, 1, 1, 1, .5, .5 onglets

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Nebido [Testosterone undecanoate injectable]

Undecanoate de testostérone - marque Nebido par Bayer n'est pas un produit de musculation mais plutôt un produit médical, unique par ses propriétés en raison d'une action extrêmement longue par rapport à l'undécanoate de testostérone oral (andriol / restandol) ou à l'androgel / testogel largement utilisé à des fins de thérapie de remplacement de la testostérone. Il se présente sous forme d'ampoules de 4 ml, contenant au total 1000 mg d'undécanoate de testostérone. La substance active est l'undécanoate de testostérone 250 mg / ml (correspondant à 157,9 mg de testostérone pure). Les autres ingrédients sont le benzoate de benzyle et l'huile de ricin raffinée. Nebido est un liquide huileux clair et jaunâtre. Le contenu des emballages est: 1 ampoule en verre ambré avec 4 ml de solution injectable. Testostérone est la principale hormone sexuelle masculine. Nebido is used for treating symptoms of testosterone deficiency, also known as hypogonadism in adult men whose testes do not produce enough of it.  Nebido works by replacing or supplementing endogenous testosterone production.Low testosterone levels should be confirmed by two separate blood testosterone measurements and include following symptoms, which Nebido intends to cure: impotence, infertility, low sex drive, tiredness, depressive moods, bone loss caused by low hormone levels. In general, mild testosterone replacement therapy is advisable for men over 40, for men over 65 it’s vitally important since endogenous production becomes critically low.

Testosterone Undecanoate peut également être utilisé pour d'autres conditions comme déterminé par votre médecin.

Dosage et utilisation - médical et musculation

Selon le fabricant, commun Nebido le dosage est une injection unique de 1000 mg toutes les 10 à 14 semaines, soit ~ 4 fois par an. Malheureusement, de nombreux médecins suivent cette demande et ce calendrier. Je ne prétends pas être plus intelligent que ces médecins, cependant, aucune étude indépendante n'a prouvé cela. De plus, la musculation est une histoire complètement différente. En tenant compte du fait que la demi-vie de l'undécanoate de testostérone est de 21 jours, en musculation monthly, bi-weekly (or even weekly?) injections are advisable to maintain testosterone level stable. I’m not saying that it’s absolutely necessary to inject bi-weekly, but in general it’s much better than taking it once every 6 or even 12 weeks as stated by manufacturer. Disregarding of what ester you use – frequent injections is the best way to keep your test levels stable. Longer half life just means that you can do it less frequent comparing, for instance, to sustanon (3 shots / week) or enanthate (2 shots / week). Dosages in bodybuilding should be much higher than medical dosages, something like 1000 mg monthly, and this is one more point to use more frequent injections than stated by manufacturer. We do not advice higher dosages of nebido, if you need more effect, just use different testosterone forms.

Mais s'il s'agit d'un problème médical, prenez de l'undécanoate de testostérone uniquement comme indiqué. Discutez du point ci-dessus avec votre médecin généraliste, mais la décision finale lui appartient. N'en prenez pas plus et ne le prenez pas plus souvent que votre médecin vous l'a prescrit. Faire cela peut augmenter le risque d'effets secondaires.

Nebido est strictement destiné à l’injection intramusculaire (de préférence dans la fesse). Des précautions particulières doivent être prises pour éviter toute injection dans un vaisseau sanguin. La testostérone est libérée progressivement tout le temps du réservoir dans la circulation sanguine et reste efficace pendant très longtemps.

Empilement

In bodybuilding stack just as regular testosterone undecanoate (andriol /  restandol) – with other safe dugs like anavar, primobolan, etc. Stacking with stronger drugs like deca will just negate it’s very-low-side-effects advantage.

Avantages de l'utilisation de Nebido

La thérapie de remplacement de la testostérone peut produire de profonds changements physiques et / ou mentaux chez les patients ayant un faible taux de testostérone. Les avantages du remplacement de la testostérone sur la fonction physique et sexuelle, les niveaux d'énergie, la masse grasse et musculaire, les lipides sanguins et la densité osseuse chez les hommes à faible taux de testostérone sont bien acceptés. Ainsi, il faut observer les effets suivants avec Nebido:

Un intérêt sexuel accru apparaît généralement après 3 semaines et se stabilise à 6 semaines
Les augmentations des érections et de la satisfaction sexuelle se produisent dans les 6 mois
Les améliorations de la qualité de vie sont nettes en 3-4 semaines et se poursuivent pendant un certain temps
L'amélioration de la dépression ou de l'humeur est notée après 3-6 semaines et atteint un maximum après 18-30 semaines
Les effets bénéfiques sur les lipides sanguins apparaissent après 4 semaines et atteignent un maximum après 6-12 mois
Les améliorations de la glycémie deviennent évidentes après 3 à 12 mois
Les changements dans la composition corporelle et la force musculaire se produisent dans les 12 à 16 semaines et se stabilisent à 6 à 12 mois
Les améliorations de la densité osseuse apparaissent après 6 mois et se poursuivent pendant au moins 3 ans
Minor changes in prostate size and a slight increase in the level of prostate-specific antigen occur with treatment, leveling off after 12 months. Any further increases may be related to normal aging rather than testosterone treatment.

Source: Début des effets du traitement à la testostérone et période de temps jusqu'à ce que les effets maximaux soient atteints. Saad F, Aversa A, Isidori AM et al. Eur J Endocrinol 2011; 165 (5): 675-685.

Temps de détection

Nebido peut conduire à des résultats positifs dans les tests de dépistage de drogues. Le temps de détection est plus long par rapport aux formes orales, malheureusement, il n'y a pas d'informations suffisantes à ce sujet.

Effets secondaires de Nebido (undécanoate de testostérone) et PCT

Le traitement avec des doses élevées de préparations de testostérone arrête ou réduit généralement la production de spermatozoïdes, bien que cela revienne à la normale après l'arrêt du traitement. L'administration à forte dose ou à long terme de testostérone augmente parfois les occurrences de rétention d'eau.

Nebido est l'éther de testostérone et les effets secondaires liés aux androgènes pourraient être un problème en théorie. Cependant, en raison de leur action légère, ces effets sont si faibles que Nebido peut être considéré comme un médicament très sûr à moins que la dose ne soit trop élevée.

Cependant, si vous observez des effets secondaires liés aux œstrogènes tels que la croissance mammaire ou les dépôts de graisse chez les femmes, commencez à utiliser le tamoxifène. Si vous jouez avec des doses élevées, le clomiphen peut être nécessaire après le cycle.

Si vous êtes diabétique, il peut être nécessaire d'ajuster votre insuline.

 

Usage féminin

L'utilisation médicale de Nebido est contre-indiquée pour les femmes et ne doit certainement pas être utilisée chez les femmes enceintes ou qui allaitent. Certaines exclusions concernent les femmes transsexuelles.

Malheureusement, nous ne pouvons pas fournir d'informations fiables sur ce sujet en musculation jusqu'à présent. L'undécanoate de testostérone par voie orale est la seule forme de testostérone, qui pourrait être utilisée par les femmes sans effets secondaires graves à une dose quotidienne de 120-240 mg, elle se combine bien avec l'anavar (oxandrolone) et, parfois, le primobolan. Cependant, avec la forme injectable de l'undécanoate de testostérone, la situation est différente car plus de testostérone est administrée dans le système (et moins gaspillée) par rapport à la forme orale, donc à notre avis, si elle est utilisée par des femmes, la posologie devrait être inférieure à celle de l'andriol.

Contre-indications

Nebido n'est pas destiné à être utilisé chez les femmes. Nebido ne doit pas être utilisé chez les enfants et les adolescents.
N'utilisez jamais Nebido:
si vous avez déjà eu un cancer androgéno-dépendant ou un cancer suspecté de la prostate ou du sein
si vous avez ou avez déjà eu une tumeur hépatique

Avant le début de la testostérone, tous les patients doivent subir un examen détaillé afin d'exclure un risque de cancer de la prostate préexistant. Une surveillance attentive et régulière de la prostate et du sein doit être effectuée (il en va de même pour tout traitement à la testostérone).

Informez votre médecin si vous avez ou avez déjà eu: épilepsie, problèmes cardiaques, rénaux ou hépatiques, migraine, interruptions temporaires de votre respiration pendant le sommeil (apnée), car ceux-ci peuvent s'aggraver;
le cancer, car le taux de calcium dans votre sang peut devoir être testé régulièrement;
problèmes de coagulation sanguine;

Si vous souffrez d'une maladie grave du cœur, du foie ou des reins, le traitement par Nebido peut entraîner de graves complications sous forme de rétention d'eau dans votre corps parfois accompagnée d'une insuffisance cardiaque (congestive).

 

Oubli d'une dose d'undécanoate de testostérone

Si vous oubliez une dose de ce médicament et votre schéma posologique, prenez la dose oubliée dès que possible. Cependant, si vous ne vous en souvenez pas avant la prochaine dose, sautez la dose oubliée et revenez à votre programme de dosage habituel. Ne doublez pas les doses.Stockage Nebido

Garder hors de la portée des enfants.
Conserver à l'abri de la chaleur et de la lumière directe à température ambiante.
Empêchez le médicament de geler.
Ne conservez pas de médicaments périmés ou de médicaments dont vous n'avez plus besoin.

 

Buy Nebido Bayer (testosterone undecanoate)

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EPO – Erythropoietin usage for endurance sportsmen

EPO - Érythropoïétine

Buy EPO (Erythropoietin) online

In this article we will describe different aspects of EPO including epo dosage for athletes
Érythropoïétine (EPO)is a naturally occurring protein hormone. EPO is produced in the body by the kidneys and is used to regulate red blood cell production.  Patients suffering from anemia or chronic renal failure are legally allowed to use this form medically, it is proven that this product effectively stimulates and maintains erythropoiesis in a large percentage of patients treated. The efficiency of this drug quickly made it a ready replacement for older and less effective therapies such as Anadrol (oxymetholone) 50 or Nandrolone Decanoate. The biological activity or rHuEPO is indistinguishable from that of human erythropoietin. Some athletes have decided to take advantage of this substance as well.Nowadays, all EPO on the market is Recombinant human erythropoietin (rHuEPO). There are five erythropoiesis-stimulating agents currently available: epoetin-alpha, epoetin-beta, epoetin-omega, epoetin-delta, and darbepoetin-alpha. Both, endogenous and recombinant EPO makes body producing more red blood cells, thus increasing oxygen transmission from lungs to all systems of the body, including muscles, which results in increased stamina in performance sports. In the medicine it cures symptoms of anemia including cancer-caused.

EPO dans le SPORT

EPO has put a whole new spin on blood doping. No need for messy transfusions, just shoot up with EPO to increase your circulating erythrocyte mass.EPO is actually not that dangerous a product to use if it is used PROPERLY, and one’s blood is monitored. With proper blood work, and boosting to a safe level (typically max of 53-54% for elite level endurance athlete, while it’s around 40% for “normal” people) there shouldn’t be major complications. But do not cross that line.

Endurance athletes are highly attracted to EPO for the effect it has on red blood cell production. It is no secret that the practice of “blood doping” is popular with endurance sports. This procedure involves removing and storing a quantity of blood from your body, to be later replaced. By adding this stored blood before an event (by then the body has restored the lost blood volume), the athlete has a much greater number of red blood cells. The blood can therefore transport oxygen more efficiently, and the athlete is given a noticeable endurance boost. This has no doubt been the difference between winning and losing for many individuals. This procedure, however, carries with it a great number of risks. Blood is a difficult thing to store and administer, not to mention the problems that can occur with the extra cell volume. Part of these risks (besides cells volume problem)  are reduced with EPO, a drug that basically equates to “chemical blood doping”. Some studies have shown that athletes have had an 9% increase in VO2 max, 7% increase in power output, and a 5% decrease in max heart rate.

While the benefits of using erythropoietin are unquestionable, there are serious side affects that an athlete needs to consider. After injection, the blood has a higher concentration of red blood cells and a thicker viscosity. This may lead to thromboembolic events that could be fatal. I.e. if you dope more than necessary, thrombs may stop the bloodstream during the exercises and sportsmen dies. There are serious suspicions against EPO for the deaths of some top cyclists during 80s and 90s. Seizures and hypertension are also demonstrated in those athletes who are blood doping. Most athletic federations have banned this practice and a hemoglobin limit of 18.5 g/dL has been implemented.

The injection of EPO in the body is a practice that would be very beneficial to any athletes involved in endurance activities. It would allow them to carry more oxygen per unit of blood than before thus improving their performance. Who can use it? All long-distance runners (800+meters), cyclists, etc., i.e. anywhere you need high aerobic stamina. EPO also increases performance and durability of all fighters and players (football, hockey players, etc.)

In a study done by Audran, nine well-trained athletes (seven males, two females) received a 50U/kg dosage of rhEPO daily for 26 days. Tested were four triathletes, two cyclists, one rower, one swimmer, and one handball player, averaging an age of 24 years old and weight of 73kg. During treatment, significant increases in reticulocyte, EPO and sTfr concentrations and sTfr/serum protein ratios were seen by day ten, whereas hemoglobin and hematocrit levels did not clearly increase until day 14. From the results after the last rhEPO injection, reticulocyte, hemoglobin and sTfr concentrations remained above baseline values for seven days; and hematocrit levels remained above baseline up to 14 days; and EPO levels stayed above baseline for two days, as was expected due to its short half-life. Physiological tests were also done to measure the effect of rhEPO. On average, VO2max increased by 5ml/min/kg, and maximum heart rate lowered by 9 beats/min after the treatment period. In simple words – athlete can take advantage on the EPO injections effect for up to two weeks, but peak level is reached just after the last injection.

 

EPO dosage for athletes

Weekly dosage varies 50-300 IU per kilogram of body weight. By this guideline a 176 lb (80 kgs) athlete would take a maximum of 4000 U per injection. This would be done in the days/weeks prior to a competition, the peak effect hopefully reached near the day of the event. Sportsmen starts feeling results after two weeks of usage (hematocrit level increases 3-4%). Most of specialists agree that one should not use erythropoietin for more than six weeks!

We find it optimal to use following schedule: Loading phase 4500-12000 IU for week 1-3 (6000 IU in average), then keep supportive dosage 3000-4000 IU for weeks 4-6.  Weekly dosage is to be split on three equal shots.

Also one can use this formula: 20-30 IU per kg for every shot (three shots a week). Conservative approach is 4500 IU / week (3 shots x 1500 IU) with 3000 IU supportive dosage (3 shots x 1000 IU).The higher dosage is – the more effect and more risks you gain. Anyway, it depends on the personal characteristics, base levels, target goals desired. Blood tests recommended if you’re toying with higher doses.

Pre-competition protocol, low detection, 30 000 IU of substance available:
Weeks 1-3, 2000UI 3x per week
Weeks 4-6, 2x1500UI +1x 1000UI per week (so total of 4000UI per week)

Pre-competition protocol, low detection, only 15 000 IU of substance
available:
Weeks 1-3, 1500UI 3x per week
Week 4, 3x 500UI per week

Take one tab of aspirin two times a day after meal or along with milk to prevent stomach damages (milk neutralizes aspirin acids). Aspirin will decrease blood viscosity thus decreasing risks of thrombosis which could be fatal during the long race due to sweating and extreme dehydration.

In general, greater dosages of rhEPO induce a quicker response of increased erythropoiesis than lower dosages, however, they are more likely to be detectable by doping tests. If athlete is not in a rush, it’s better to make three shots a week – peak form will be achieved anyway.

Injecting EPO

EPO is sold in recombinant form (rhEPO) for injection. It usually is packaged as a lyophilized (freeze dried) powder that is reconstituted with sterile water before injection. Injections preferably to be made by thin needle with insulin syringes. Erythropoietin is to be given subcutaneously (between the skin and muscle – into the body fat) or intravenously. These two paths of administration have greatly different effects on the blood level of the drug. When given as an IV injection, peak blood levels of the drug are reached very quickly. The half-life is also short, approximately 4 or 5 hours long. When administered “SubQ”, the drug will take 12 to 18 hours to reach a peak level. Given an equal dose, this concentration will also be much lower than the intravenous method. The half-life also greatly extended, estimated to now be approximately 24 hours.

SubQ injections are to be made in the outer upper arms, front of thighs, or abdomen. If you are injecting in the abdomen, just be sure to not be too close to the umbilicus. If you’re doing some anticoagulant as well, you could still give EPO in the abdo, just not in the same site. EPO injections often burns because you inject it cold. If you can roll it between your hands a couple of minutes or let it get to room temperature, it is painless as an insulin injection.

 

EPO empilable

Be extremely careful if you are going to use Erythropoietin (EPO) along with anabolic steroids, this can be a dangerous chem to mess with, especially with erythropoetesis-stimulating drugs like Anadrol.

Some endurance athletes may use both, EPO and winstrol during preparation for the contest, however, we have no information on the possible synergetic effects, and, most important, side effects. If anyone emails us his own winstrol + Erythropoietin (EPO) experience – this would be appreciated.

With high dosages anticoagulant therapy such as Lovenox is indicated to help reducing the risk of developing DVT, or deep vein thrombosis. For regular dosages aspirin is enough.

In practice, it is common for rhEPO injections to be accompanied with intravenous injections or oral supplementation of iron (orals are more effective). However, Iron overload may occur and lead to symptoms similar to those of genetic hemochromatosis. Folic asid and Vitamins also advisable.

Here’s possible EPO stack (weekly dosage!):  100 IU/kg of rhEPO; 25mg of iron, 25mg of folic acid; 2500mcg of Vitamin B12, lenght of treatment 10-20 days, 2-3 shots per week.

 

Contrôle antidopage et EPO

Until recently, accurate testing has been difficult because the recombinant human EPO made in the lab is virtually identical to the naturally occurring form and there are no firmly established normal ranges for EPO in the body. The only previously available route to curtail cheating for sports governing bodies was to ban an athlete if the hematocrit level was too high (e.g., above 50%). Thus, in the past many athletes chose to cheat because, as long as they kept their hematocrit levels below 50%, there seemed little risk of getting caught. Of course, the other way to get caught was highlighted in the disastrous 1998 Tour de France. Several team doctors and personnel from several teams were caught red-handed with thousands of doses of EPO and other banned substances. Ultimately about 50% of the teams withdrew from the race – either for cheating or in protest.

Unfortunately, testing technology has now notably improved. There are now accurate urine and blood tests that can detect the differences between normal and synthetic EPO. This test became the standard one and was the sole means to detect for EPO use in the 2004 Athens Olympic Games. The reliability of this test helps explain the cascade of athletes who have been caught. Therefore, at the present, athlete must consider “window” – just like with steroid use – when chances to detect falls down, but effect is still considerable. I.e. at the moment of competition, EPO should move out of the system but red blood cells should be still in.

There are short-acting and long-acting types of EPO (we offer short-acting version). It’s better to take smaller doses on regular basis than single big injection. This reduces the possibility of detection by the urine test by lowering the percent of basic isoforms  in the urine. A smaller dose means a drug tester might only have 12 hours to detect the last injection, and given the fact that drug tests aren’t usually carried out in the middle of the night, this leaves only a very small window open for being tested “positive”. Taking small, regular doses also simulates the body’s natural physiology more closely than a super-sized dose, which means that it could even get under the radar for the longer term blood testing.  So 2000 IU three times a week is better than 6000 IU once a week.

Detection time varies 12-48 hours according to different sources (in fact you might be in danger even longer with high dosages). Most likely it also highly depends on the  dosage and cycle schedule. Fortunately, rhEPO has a short half-life and is similar in structure to endogenous EPO. These two factors make blood and urine detection difficult since electrophoretic techniques must be done within a limited timeframe in order to be able to distinguish between the two forms of erythropoietin.

So, what is this test? It is possible to detect rhEPO in urine and blood serum as was done by Wide. He tested 15 healthy, moderately-trained men between the ages of 19 to 40 years old. At a fairly low dosage, 20U/kg three times a week for eight weeks, rhEPO was accurately detected in blood up to two days after the last injection; and in urine one day after the last injection. From the data, sensitivity of the test decreases to fifty percent in detecting rhEPO in blood or urine after three days from the last injection

In order to gain the physiological effects of rhEPO, athletes need to continue its use until a late stage of preparation for an event. A test for increased erythropoiesis in the two to six weeks before competition would have a high likelihood of detecting rhEPO abuse – they can catch you during preparation.

 

Risks and side effects with EPO

Just like with steroids – you should use it wisely. Inappropriate usage might be dangerous if not fatal, but proper one eliminates all the risks or lowers it to the affordable level. Nowadays, we gained enough experience and stats to know how to avoid the problems.

The reason that EPO, and transfusion blood doping, might be dangerous is because of increased blood viscosity. Basically, whole blood consists of red blood cells and plasma (water, proteins, etc.). The percentage of whole blood that is occupied by the red blood cells is referred to as, the hematocrit. A low hematocrit means dilute (thin) blood, and a high hematocrit mean concentrated (thick) blood. Above a certain hematocrit level whole blood can sludge and clog capillaries. If this happens in the brain it results in a stroke. In the heart, a heart attack. Unfortunately, this has happened to several elite athletes who have used EPO in 80es.

EPO use is especially dangerous to athletes who exercise over prolonged periods. A well-conditioned endurance athlete is more dehydration resistant than a sedentary individual. The body accomplishes this by several methods, but one key component is to “hold on” to more water at rest. Circulating whole blood is one location in which this occurs and, thus, can function as a water reservoir. During demanding exercise, as fluid losses mount, water is shifted out of the blood stream (hematocrit rises). If one is already starting with an artificially elevated hematocrit then you can begin to see the problem – it is a short trip to the critical “sludge zone” (so drink enough liquids and don’t forget about aspirin!).

Additional dangers of EPO include sudden death during sleep, which has killed approximately 18 pro cyclists in the past fifteen years, and the development of antibodies directed against EPO. In this later circumstance the individual develops anemia as a result of the body’s reaction against repeated EPO injections (so do not use for longer than 6 weeks! and do not use through the whole year, do it 1-2 times before the most important competitions).

There are also a number of side effects associated with general use of this substance. Most notable, blood pressure can begin to rise as cell volume changes. This can reach the point of headaches and high blood pressure, obviously an unwanted effect. Additionally, flu-like symptoms, aching bones, chills and injection site irritations are also possible. Since athletes are not using this product for a medical condition, a strong incidence of side effects should be an indicator to discontinue using the drug. Clearly one should not wish to compromise their health for an athletic push.

 

Does EPO contain blood fractions?

While erythropoietin itself is not a blood product, some brands of the synthetic form do have a very small amount of a blood fraction added to them. The epoetin-alfa formulation (Epogen®, Procrit®) contains 2.5 mg human serum albumin. The albumin first prevents the pharmaceutical from sticking to the vial, and then acts as a carrier molecule to help the EPO remain in the bloodstream until it reaches its destination at the bone marrow.

 

Pharmacology

Stimulates RBC (red blood cells) production.
Pharmacokinetics
Absorption

T max is 5 to 24 hours (subcutaneous).
Elimination

Elimination half-life is approximately 4 to 13 hours (IV).

 

Special Populations

Elderly: Pharmacokinetic data indicate no apparent difference in half-life among adult patients older or younger than 65 yr of age.
Children: Pharmacokinetic profile in children and adolescents is similar to that of adults. Limited data are available for neonates.

 

What alternatives to EPO are there?

EPO is the standard of care for many patients with anemia of end-stage renal disease (ESRD). For certain patients, such as those who produce antibodies to erythropoietin, who develop pure red cell aplasia (PRCA), or who develop arterial hypertension, treatment with any form of EPO is not appropriate. However, these patients may be given androgens (hormones) that have been shown to stimulate bone marrow function. Of course, as with any medicine, these substances are not without side effects of their own. One of the most widely used of these is nandrolone decanoate (NAND), which seems to be better tolerated with less dramatic side effects than other androgenics.

In some cases, intravenous iron without EPO appears to be as effective in correcting anemia.

 

Medical Indications and Usage

Below we’ll provide some information for medical EPO (erythropoietin) usage. Please use this for information purposes only! We can give advices in sport, but not with life-threatening deceases. We do not to harm anybody by improper advice, make sure to contact your GP before usage!!!

So, where it is used in medicine? Treatment of anemia related to chronic renal failure (CRF), anemia related to zidovudine therapy in HIV-infected patients, and anemia due to chemotherapy in patients with metastatic non-myeloid malignancies; reduction of allergenic blood transfusions in surgery patients.

Kidney disease patients : Recombinant human erythropoietin was first approved as an adjunct in the treatment of kidney disease patients on hemodialysis, in whom anemia is an inevitability due to both the disease and the dialysis.
AIDS patients : Approval was also given for it to be given to AIDS patients on AZT (ziduvidene).
Red cell production : Its use is increasing in preoperative and postoperative settings to stimulate the surgical patient’s red cell production.
Acute surgical and post-op : It may be of benefit in acute surgical settings, and may permit more rapid recovery in the post-op period. In particular, it may be a useful adjunct following perioperative hemodilution.
Chemotherapy : It is also gaining currency in the treatment of anemia secondary to chemotherapy for cancer.
Blood transfusion alternative : In many clinical settings EPO may be used to reduce or even eliminate the need for blood transfusion. It can be used in neonates for treatment of anemia of prematurity. Various clinical applications for EPO and a succinct historical perspective of erythropoietin are presented and discussed in research by T. Ng, et al. (2003).
Other potential benefits : There is evidence to show that, in addition to boosting RBC production, EPO may have a positive effect on platelet and leukocyte production. EPO has also demonstrated a tissue-protective ability, of particular benefit in chronic heart failure and neurological damage, and may benefit surgical and burn patients through its wound healing properties.
Unlabeled Uses: Anemia associated with critically ill patients, CHF, chronic disease (eg, rheumatoid arthritis), postpartum anemia, sickle cell disease, thalassemia, multiple myeloma, Jehovah’s witnesses (due to prohibition of human blood transfusion), radiation treatment, epidermolysis bullosa, porphyria, for athletic enhancement (yes, that’s our case!), sexual dysfunction, transfusion iron overload, uremic pruritus.
Contraindications: Hypersensitivity to mammalian cell–derived products or human albumin; uncontrolled hypertension.

 

Medical Dosage and Administration of EPO

The optimal dosing regimen has yet to be defined. The authors of some studies favor lower doses such as 75 to 150 IU for every kilogram (u/kg) of body weight given daily or every other day. Others found that 600 u/kg given once a week was more effective. Nevertheless, the most commonly ordered dose is likely to be 300 u/kg three or four times a week. Thus, for a 70 kg patient, 60,000 IU per week would be ordered.

 

Cancer Patients EPO usage

Adultes

Subcutaneous 3 times/wk dosing: 150 units/kg 3 times/wk. Reduce the dose by 25% when Hgb reaches a level needed to avoid transfusion or increases more than 1 g/dL in any 2-wk period. Withhold the dose when Hgb exceeds a level needed to avoid transfusion and restart at 25% below the previous dose when the Hgb approaches a level where transfusions may be required. Increase the dosage to 300 units/kg 3 times/wk if the response is not satisfactory after 4 wk to achieve and maintain the lowest Hgb levels sufficient to avoid the need for RBC transfusion and not to exceed the upper safety limit of 12 g/dL. Discontinue if after 8 wk there is no response as measured by Hgb levels or if transfusions are still required. Weekly dosing: 40,000 units/wk. Reduce the dose by 25% when the Hgb reaches a level needed to avoid transfusion or increases more than 1 g/dL in any 2-wk period. Withhold the dose if the Hgb exceeds a level needed to avoid transfusion and restart at 25% below the previous dose when the Hgb approaches a level where transfusion may be required. Increase the dosage to 60,000 units/wk if the response is not satisfactory (no increase in Hgb by at least 1 g/dL after 4 wk of therapy, in the absence of an RBC transfusion) to achieve and maintain the lowest Hgb levels sufficient to avoid the need for RBC transfusion and not to exceed the upper safety limit of 12 g/dL. Discontinue if after 8 wk there is no response as measured by Hgb levels or if transfusions are still required.
Children

IV Weekly dosing: 600 units/kg/wk (max, 40,000 units/wk). Reduce the dose by 25% when the Hgb reaches a level needed to avoid transfusion or increases more than 1 g/dL in any 2-wk period. Withhold the dose if the Hgb exceeds a level needed to avoid transfusion and restart at 25% below the previous dose when the Hgb approaches a level where transfusion may be required. Increase the dosage to 900 units/kg/wk (max, 60,000 units/wk) if the response is not satisfactory (no increase in Hgb by at least 1 g/dL after 4 wk of therapy, in the absence of a RBC transfusion) to achieve and maintain the lowest Hgb levels sufficient to avoid the need for RBC transfusion and not to exceed the upper safety limit of 12 g/dL. Discontinue if after 8 wk there is no response as measured by Hgb levels or if transfusions are still required.
CRF EPO usage
Adultes

IV / Subcutaneous Individually titrate to achieve and maintain Hgb levels between 10 and 12 g/dL. Increases in dose should not be made more often than once monthly. Start with 50 to 100 units/kg 3 times/wk. Increase the dose by 25% if the Hgb is less than 10 g/dL and has not increased by 1 g/dL after 4 wk of therapy or if the Hgb decreases below 10 g/dL. Reduce the dose by 25% when the Hgb approaches 12 g/dL or the Hgb increases by more then 1 g/dL in any 2-wk period. If the Hgb continues to increase, temporarily withhold the dose until the Hgb begins to decrease, then reinitiate treatment at a dose approximately 25% below the previous dose.
Children

IV / Subcutaneous Individually titrate to achieve and maintain Hgb levels between 10 and 12 g/dL. Increases in dose should not be made more often than once monthly. Start with 50 units/kg 3 times/wk. Increase the dose by 25% if the Hgb is less than 10 g/dL and has not increased by 1 g/dL after 4 wk of therapy or if the Hgb decreases below 10 g/dL. Reduce the dose by 25% if Hgb approaches 12 g/dL or the Hgb increases by more then 1 g/dL in any 2-wk period. If the Hgb continues to increase, temporarily withhold the dose until the Hgb begins to decrease, then reinitiate treatment at a dose approximately 25% below the previous dose.
Surgery EPO usage
Adultes

Subcutaneous Prior to starting treatment, obtain Hgb to establish that it is more than 10 to less than 13 g/dL.

Usual dosage: 300 units/kg/day for 10 days before surgery, on the day of surgery, and for 4 days after surgery.

Alternative dose schedule: Subcutaneous 600 units/kg in once-weekly doses (21, 14, and 7 days before surgery), plus a fourth dose on the day of surgery.
EPO usage on Zidovudine-Treated, HIV-Infected Patients
Adultes

IV / Subcutaneous Prior to starting therapy, determine the endogenous serum erythropoietin level. Evidence suggests that patients receiving zidovudine with endogenous serum erythropoietin levels more than 500 milliunits/mL are unlikely to respond to epoetin alfa therapy. Titrate the epoetin alfa dosage to achieve and maintain the lowest Hgb level sufficient to avoid the need for blood transfusion and not to exceed the upper safety limit of 12 g/dL. For patients with serum erythropoietin levels of 500 milliunits/mL or less who are receiving zidovudine 4,200 mg/wk or less, the recommended starting dosage is epoetin alfa 100 units/kg 3 times/wk for 8 wk. Monitor the Hgb weekly. If the response is not satisfactory in terms of reducing transfusion requirement or increasing Hgb after 8 wk of therapy, the dosage of epoetin alfa can be increased by 50 to 100 units/kg 3 times/wk. Thereafter, evaluate the response every 4 to 8 wk and adjust the dose accordingly, in 50 to 100 units/kg increments 3 times/wk, to a dosage of epoetin alfa 300 units/kg 3 times/wk. After attaining the desired response, titrate the epoetin alfa dose to maintain the response. If the Hgb exceeds the upper safety limit of 12 g/dL, stop until the Hgb drops below 11 g/dL. Reduce by 25% when treatment is resumed and titrated to maintain the desired Hgb.

 

General Medical Advice on EPO

For subcutaneous or IV bolus administration only. Not for intradermal, IM, or intra-arterial administration. IV route recommended for patients on hemodialysis.

Do not shake or vigorously agitate vial. Prolonged vigorous shaking may denature the glycoprotein, rendering it biologically inactive.

Do not administer if particulate matter, cloudiness, or discoloration is noted.

If transferring saturation is less than 20%, give supplemental iron.

IV dose may be administered into venous line at end of dialysis procedure to obviate need for additional venous access.

Rotate subcutaneous injection sites.

Single-dose vials contain no preservative. Use only 1 dose/vial. Do not reenter vial. Discard any unused portion. Do not combine unused portions or save unused portions for later use.

Do not administer in conjunction with other drug solutions. However, at time of subcutaneous administration, single-use vials may be admixed in a syringe with bacteriostatic sodium chloride 0.9% with benzyl alcohol 0.9% at a 1:1 ratio. Multidose vials contain benzyl alcohol and admixing is not necessary.

Adjust dose to achieve and maintain lowest Hgb level sufficient to avoid the need for RBC transfusion and not to exceed 12 g/dL.

Storage/Stability: Store vials in refrigerator (36° to 46°F). Do not freeze or shake. Protect from light. Multidose vials may be stored in refrigerator at 36° to 46°F for up to 21 days after initial entry.

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Proviron (DHT, Masterlone, Masterolone, Mesterolone)

Proviron (Masterolone) est une forme orale de 1-méthylé DHT (methyl-dihydrotestostérone). This is very strong androgen which is 3-4 times more effective than “normal” testosterone, it possesses no anabolic characteristics and no capabilities of converting to estrogen. One would imagine then that mesterolone would be a perfect drug to enhance strength and achieve some progress. Unfortunately, there is a control mechanism for DHT in the body. When levels get too high it is being converted to an inactive compound. This inactive compound can equally be transformed in the opposite direction to dihydrotestosterone by the same enzyme when low levels of DHT are detected. But this means that very large amounts of this substance are useless to achieve muscle hypertrophy. Very common usage is fighting estrogen just like with Tamoxifen Citrate or Clomiphen. Provironhas four distinct applications in bodybuilding.First of all, proviron serves as anti-estrogen, it prevents  aromatization of other steroids as a process and also partially blocks estrogen receptors. In this instance its action differs from tamoxifen, which only blocks  estrogen receptors. Thus side effects such as gynecomastia and increased water retention are successfully eliminated. Proviron hits the root of the problem, while Tamoxifen fights only symptoms and should be used for longer period until all excessive estrogens are washed out of the body.
The second application is based on expanding the capacity of testosterone. 97-98% of testosterone in the body of a healthy person is inactive and bound to certain proteins. Proviron in this case replaces testosterone, thus more of latter is being released into the blood and helps to build muscle mass.

Thirdly, mesterolone is added in pre-competition cycles to increase the rigidity and quality muscle volume. It also decreases water retention in the body, giving the user a visual effect of a dry, high-quality, lean muscles. Proviron is often used not only among bodybuilders, but even the actors and models, who use it to acquire the necessary sportive form  before the shooting. Just like the another methylated DHT structure called drostanolone, mesterolone is particularly strong in achieving this effect.Finally, Proviron is used for recovery of sexual activity during the cycles of steroids such as trenbolone and nandrolone, which decrease libido. Proviron is also commonly prescribed by doctors for people with low levels of testosterone, or patients with chronic impotence.Mesterolone is preferred by many athletes because it has virtually no side effects on men. In large doses it can cause some virilization symptoms in women. Doses of 25 and 250 mg per day shall be applied without adverse effects. 50 mg per day is usually sufficient to reach goals for any of four applications that we mentioned above. Thus, there is no need to increase the dose.

Les athlètes masculins devraient préférer Proviron à Nolvadex. Avec Proviron, l'athlète atteint une meilleure dureté musculaire, car le niveau d'androgènes est augmenté et la concentration d'œstrogène reste faible. Cela est particulièrement évident lors de la préparation d'une compétition en conjonction avec un régime.

Cependant, il faut être conscient que la perte de force causée par la diminution de la production naturelle de testostérone après le cycle n'est pas guérie. L'athlète doit utiliser d'autres médicaments comme HCG et clomiphen pour cela.

Dosage et utilisation

Proviron est un composé très efficace, la posologie quotidienne de 50 mg est suffisante bien que certains hommes en fassent 100 et même 250 mg / jour. L'athlète prend normalement un comprimé de 25 mg le matin et l'autre le soir. Dans certains cas, même un comprimé de 25 mg suffit. L'association de 50 mg de Proviron par jour et de 20 mg de Nolvadex par jour entraîne une suppression presque complète des œstrogènes. Cependant, gardez à l'esprit que l'œstrogène n'est pas un mal absolu, il joue également un rôle important dans la construction musculaire. La suppression complète des œstrogènes signifie des gains plus faibles, il faut donc garder un équilibre et diminuer le niveau d'œstrogènes uniquement au point où il n'y a pas d'effets secondaires mais en produit toujours des positifs.

In the past athletes used it throughout the whole season to make dry and fit outlook all the time, however, we don’t advice such practices nowadays. Clenbuterol / albuterol (ventolin) can do the same but with less side effects.

Empilement

Proviron is an oral 1-alpha-alkylated substance mostly used as  an anti-estrogen drug. Mesterolone may actually contribute to gains.  It is taken daily in 50-100 mg doses.

The best stack is certainly with testosterone. This results in qualitive, lean gains as free testosterone levels are increased and less converted to estrogen.

Bien sûr, le proviron est également utilisé dans de nombreuses autres piles, par exemple avec le dianabol (méthandrosténolone), l'undécanoate de boldénone et la nandrolone afin de réduire les activités liées aux œstrogènes et d'augmenter la dureté musculaire.

Combo of proviron with boldenone makes dead lock for a cutting stack. Sometimes it’s even become possible to add deca into that cutting stack, preferably along with winstrol. It’s good idea to use proviron with nandrolone, because nandrolone temporarily decreases libido.

Temps de détection

2 mois

Effets secondaires avec proviron

When athlete do it for more than 10-12 weeks it may slightly increase liver values although in general proviron is well tolerated by it. Side effects of Proviron for men with a dose of 2 – 3 tablets are very small, so that Proviron, in combination with a steroid cycle can be relatively safe to be taken over several weeks.

DHT can increase blood pressure. High dosages may lead to premature baldness and sexual overstimulation, which leads to prolonged erection. Since this state is painful and can cause penis damage, it makes sense to reduce the dose or discontinue its use altogether.

Only 34% of recipients observe minor decrease in endocrine glands function. Proviron did not stop work of HPTA (glands) for noone who took the drug for a year at a dose of 150 mg / day. In general it’s pretty safe and has little impact on the work of HPTA.

Il n'y a pas d'effet sur le taux de LH (hormone lutéinisante) et de FSH (hormone stimulante) à une posologie de 100 à 150 mg / jour.

Proviron ne remplace pas Clomid comme traitement hormonal, mais ne cause pas non plus de problèmes.

L'impact de la mestérolone ne produit aucun changement dans les niveaux de stéroïdes, d'hormones thyroïdiennes, de gonadotrophines et de prolactine.

Usage féminin

Les athlètes féminines doivent être prudentes lors de l'utilisation de Proviron, car il n'exclut pas tous les effets secondaires androgènes possibles. Il est conseillé aux femmes de ne pas prendre plus d'un comprimé de 25 mg / jour. Des doses plus élevées et une utilisation prolongée pendant plus de 4 semaines augmentent les risques de virilisation. Les athlètes féminines qui n'ont pas de problème avec Proviron obtiennent de bons résultats en prenant 25 mg de Proviron par jour et 20 mg de Nolvadex par jour. Ils disent qu'en combinaison avec un régime, il accélère la combustion des graisses et le durcissement rapide des muscles.

Female athletes who naturally have higher estrogen levels,  often add Proviron to steroid cycle, which results in increasing of muscle density. In the past female athletes did proviron whole year in order to look lean, especially before contests and starring. Nowadays, clenbuterol / albuterol do the same work, because they do not cause virilization effects.

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Turanabol oral (Turanol, Turinabol, chlordéhydrométhyl-testostérone)

L'effet androgène du médicament est assez faible (6 sur 100), mais en combinaison avec un effet anabolisant (54 sur 100), Turanabol (Turinabol) devient un médicament extrêmement efficace. Par exemple, dianabol a un effet androgène 43/100 et un effet anabolisant 90/100, mais, à son tour, le dianabol a beaucoup plus d'effets secondaires et inacceptables pour les sportifs de haut niveau comme les coureurs ou les cyclistes. Avec Turanabol, vous n’aurez pas de problèmes de poitrine hypertrophiée, d’excès d’œstrogènes ou de perspectives aqueuses et gonflées comme avec le dianabol.

La drogue turinabol (turanabol) a été inventé en Allemagne de l’Est et a été utilisé pour la première fois dans la pratique médicale en 1965. Un an plus tard, il a été pleinement appliqué dans le sport. Au début, les utilisateurs étaient uniquement des hommes, mais depuis 1968, un nouveau médicament a été introduit pour la préparation des femmes. L'utilisation de Turinabol oral a été minutieusement documentée. Un document secret datant de 1973 indique que les résultats des femmes au lancer du poids ont augmenté d'environ deux mètres (!) grâce à l'utilisation de seulement deux exercices oraux. Turinabol comprimés (10 mg/comprimé) par jour pendant 11 semaines. Les résultats augmentaient avec le dosage et la durée d'utilisation. En 1972, l'utilisation orale du turinabol en Allemagne de l'Est s'est répandue dans de nombreux autres sports où la vitesse et la force étaient nécessaires, outre l'athlétisme, où il a été initialement introduit.

Voici un petit tableau qui montre clairement les effets du turinabol oral sur l’amélioration des résultats des athlètes.

Hommes femmes
Lancer du poids 2,5-4 m / 4,5-5 m
Lancer du disque 10-12 m / 11-20 m
Lancer du marteau 6-10 m
Javelot 8-15 m
Courir à 400 m 4-5 sec
Courir à 800 m 5-10 sec
Courir à 1 500 m 7-10 sec

Impressionnant, n'est-ce pas ?

Turanabol – Qu’est-ce que c’est ?

Le turinabol oral est en fait une version de la méthandrosténolone avec un atome de chlore supplémentaire en quatrième position. Le nom officiel du turinabol est donc 4-chloro-alpha-dihydrométhyltestostérone. Cette mise à niveau a rendu le médicament pratiquement non aromatisé. De plus, les métabolites du turinabol quittent très rapidement le corps, ce qui constitue un énorme avantage contre la menace des tests de dopage.

Comme la grande majorité des AAS oraux, le turinabol oral est 17-alpha alkylé et est donc potentiellement nocif pour le foie. Cependant, aucun effet négatif sur le foie n’a été signalé, même après une utilisation prolongée.

Le turinabol oral ressemble suffisamment à la méthandrosténolone, non seulement sur la structure de la molécule, mais l'action des deux médicaments est également très similaire. Turinabol produit moins de gains, mais c’est de la « qualité », de la masse maigre et il produit également moins d’effets secondaires. Bien que le turinabol ne s'aromatise pas et soit un médicament assez doux, une utilisation prolongée peut provoquer la suppression de la sécrétion de testostérone endogène, mais dans une bien moindre mesure que la méthandrosténolone (dianabol) et il est facilement rajeuni.

Turinabol oral et turinabol injectable en musculation

La différence entre le turinabol oral et injectable est comme avec la plupart des autres stéroïdes. La version orale est plus facile à prendre, mais en théorie, elle peut être nocive pour le foie. On peut donc supporter des doses plus élevées de version injectable. De plus, les injectables sont légèrement plus détectés. Mais en général, c’est une question de préférences personnelles.

En musculation, Turinabol peut être qualifié de débutant. Ce n’est pas surprenant : dans le passé, le « roi pharmacologique » en Europe de l’Est était la méthandrosténolone (dianabol), relativement bon marché. Tout le turinabol importé clandestinement d'Allemagne de l'Est a été capturé par des entraîneurs d'athlétisme léger. L’Europe occidentale et les États-Unis ne savaient même pas qu’un tel produit existait, du moins aucun bodybuilder n’a déclaré l’avoir jamais utilisé. La situation a changé il n'y a pas si longtemps, lorsque ce médicament très utile a reçu une seconde chance et a connu un succès retentissant sur le marché américain et peu après dans tous les autres pays.

Quelles sont les raisons de ce succès ? Dans un premier temps, Turinabol augmente considérablement la puissance. Deuxièmement, comme cela a été dit, le turinabol oral quitte rapidement le corps et n’est plus présent dans l’urine dans les 6 à 8 jours suivant la fin de son utilisation. Nous n’avons entendu parler d’aucun contrôle antidopage positif pour le turinabol. Cependant, il se peut que de tels tests ne soient tout simplement pas effectués de nos jours.

Une caractéristique positive du médicament peut être considérée comme donnant de la dureté aux muscles sans aucune accumulation significative d’eau. L'expérience montre que l'utilisation du turinabol est presque obligatoire dans les piles de préparation aux concours. Il remplit également la tâche de protection de la masse musculaire contre la destruction après des cycles de gonflement.

Il y a une autre caractéristique du turinabol : c'est une « drogue sexuelle ». Ce stéroïde augmente assez rapidement la libido chez les hommes, parfois trop, de sorte que le désir sexuel prévaut sur le désir d'entraînement. 🙂 Cette propriété, ainsi que la capacité d'inhiber légèrement la production de testostérone endogène, en font un médicament utile à prendre à des doses modérées entre les cycles de SAA « lourds » pour maintenir la libido.

Dosage et utilisation

Turanabol est principalement utilisé pour développer la masse maigre et la force sans rétention d’eau, ce qui se produit souvent avec Daianabol et la testostérone. Les résultats avec Turanabol dépendent directement de la dose quotidienne, qui varie normalement entre 20 et 100 mg. Les athlètes de moins de 90 kg ne ressentent aucun effet secondaire à 20 mg par jour et les athlètes plus lourds adoptent facilement 40 à 50 mg par jour.

Lorsqu'il est administré à 50 mg/ED, il augmente considérablement la masse musculaire sèche, la force, et tout cela sans rétention d'eau, ce qui peut provoquer de graves effets secondaires dus à l'activité œstrogénique. En raison de ces caractéristiques, Turanabol est un produit très efficace pour les haltérophiles. Afin d'augmenter les résultats à la fin du cours, il est recommandé d'associer ce médicament avec Parabolan (200 mg par semaine) ou avec Stanozolol (150 mg par semaine). C’est également un très bon combo pré-compétition. La combinaison ci-dessus nous permet de créer un soulagement et de développer des muscles sans aucun brûleur de graisse supplémentaire et garantie contre les effets secondaires tels que la gynécomastie et l'excès d'œstrogènes.

En athlétisme léger, la posologie est la suivante : le poids corporel en livres divisé par 10. Pour les bodybuilders, la posologie est la suivante : le poids corporel en kilogrammes divisé par 1,5 à 2 (normalement, c'est 1,5 fois plus que votre dose quotidienne de dianabol).

Le produit peut être appliqué une fois par jour le matin ou divisé en deux applications – matin et soir.

Empilement

C'est bon pour les sportifs de performance, les haltérophiles ou les bodybuilders sur des piles de coupe. Mais si une combustion sérieuse des graisses est nécessaire, cela n’aidera pas car il s’agit d’un stéroïde et non d’un pur brûleur de graisse.

1) Turanabol 35 mg/ED pendant trois semaines en fin de cycle déca-dianabol-testostérone pour apporter un soulagement

2) Turanabol 50 mg/ED pendant 6 semaines avec Parabolan (200 mg/w) et/ou Stanozolol (150 mg/w) en fin de cycle pendant 2-3 semaines (éventuellement dès le début du cycle)

3) Cycle autonome de Turanabol 50 mg/ED pendant 6 semaines. Masse maigre / pile pré-compétition.

4) Lors de la préparation des piles, le turinabol est souvent associé à du trenbolone, de l'oxandrolone ou du stanozolol. De très bons résultats sont obtenus en association avec le propionate de testostérone.

5) L’association turinabol oral + oxandrolone est trop faible, elle ne peut être recommandée qu’aux femmes.

6) Vous pouvez utiliser le turinabol oral et injectable pendant le cycle de prise de masse dans diverses combinaisons, par exemple avec de la testostérone, de la nandrolone ou une combinaison de celles-ci, au lieu de la méthandrosténolone (dianabol). Il est recommandé aux athlètes qui souhaitent obtenir des muscles de qualité.

Le PCT est nécessaire après la plupart de ces cours

Temps de détection

Il y a une grande controverse à ce sujet. Certaines sources indiquent que le dépôt du turinabol est détectable jusqu'à 18 mois et que le turinabol oral est détectable jusqu'à 12 mois dans le pire des cas. D'autres personnes sur les forums disent que 6 à 8 semaines sont plus que suffisantes. Cependant, nous ne pouvons pas comprendre d’où ils ont tous tiré des chiffres aussi énormes et peu fiables. Les tests de dopage montrent rarement la chlordéhydrométhyl-testostérone est en effet largement utilisée dans les années 60 et 70. Il existe donc de bonnes preuves que les temps de détection réels sont beaucoup plus courts. Très probablement, cette erreur s’est produite parce que les athlètes ont utilisé des substances à longue durée de vie comme le déca long. Ou, peut-être, ces sources dénaturent le turinabol avec le même déca, nous avons vu certaines descriptions de produits, soi-disant faites pour le turanabol mais après lecture, nous avons compris qu'elles étaient simplement copiées à partir des descriptions de déca, stupide, n'est-ce pas ? Aussi, tout comme un brainstorming : OUI, il quitte rapidement le corps et n'est pas détectable dans les analyses d'urine, mais les tests sanguins modernes peuvent probablement le détecter plus longtemps, en particulier lors de l'utilisation du turinabol injectable.

Il est donc difficile d'en être absolument sûr, mais nous nous en tenons à l'idée que Turinabol oral sort du corps dans les 5 à 8 jours après la fin du cycle (s'il s'agissait d'un cycle autonome de turanabol jusqu'à 100 à 150 mg/ED) et tout test de dopage urinaire montre des résultats négatifs. Ok, si les risques liés aux tests sont trop élevés et que vous êtes trop nerveux, arrêtez Turanabol 2 semaines avant le concours pour en être sûr. 2 mois sont probablement suffisants même pour turinabol injectable et des tests sanguins sophistiqués.

Un autre point positif est qu'à l'heure actuelle, les tests de dopage n'incluent plus du tout le turinabol, car il est considéré comme un médicament qui a cessé d'être utilisé après le décès de l'Allemagne de l'Est. Malheureusement, avec sa popularité croissante, il pourrait un jour revenir en arrière, comme cela s'est produit avec le genabolom (norboleton) lors des Jeux Olympiques de 2000.

Effets secondaires et PCT (thérapie post-cycle) avec Turanabol

Les effets secondaires de ce médicament dépendent des dosages ou des caractéristiques personnelles de l'athlète. Les femmes ressentent généralement des effets secondaires de virilisation suite à une utilisation prolongée du médicament à des doses supérieures à 20 mg par jour. Chez les hommes, les effets secondaires surviennent très rarement car l’activité œstrogénique du médicament est assez faible. Un cycle de six semaines ne produit aucun effet négatif, mais normalement, on peut l'utiliser encore plus longtemps.

En prenant 20 mg par jour, la production endogène de testostérone commence à être supprimée après dix jours. Cependant, il ne descend qu'à 60-70% (par exemple, Dianabol le supprime à 30-40%), ce qui explique le rajeunissement rapide par la suite. Seulement 5 jours après la fin du cycle, la production naturelle de testostérone se normalise. 7 jours après le cycle, la production endogène de testostérone peut même devenir plus élevée (!!!) qu'avant le cycle.

Des doses élevées de version orale du turanabol peuvent entraîner une augmentation des valeurs hépatiques, une certaine protection comme Liv-52 est donc nécessaire. Cependant, ce n’est pas le cas lors de l’utilisation du turanabol injectable.

D'autres effets secondaires tels que la gynécomastie, la rétention d'eau, l'hypertension artérielle, l'acné, des douleurs gastro-intestinales et un comportement agressif incontrôlé sont très peu probables.

Une augmentation de la libido au cours du cycle se produit pour les deux sexes.

Le PCT n’est pas absolument nécessaire s’il est utilisé seul, mais souhaitable s’il est utilisé à plus de 20 mg par jour. Dans ce cas, le clomid (clomifène) est préféré au nolvadex (citrate de tamoxifène). Prenez 3 comprimés (150 mg) de clomifène le 1er jour après le cycle, et 2 comprimés/ED pendant deux semaines supplémentaires (vous pouvez réduire à 1 comprimé/ED à la fin du PCT)

Usage féminin

Le Turinabol oral est un médicament relativement sûr pour les femmes à des doses ne dépassant pas 20 mg par jour et s'il est utilisé pendant 4 à 5 semaines maximum. Selon de nombreuses études, dans de telles conditions, il ne provoque pas d'effets de virilisation.

La combinaison de turinabol oral + oxandrolone convient bien aux femmes.

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Dépôt Winstrol (StanoJect, Stanozolol, Stanabol, Stromba, StrombaJect)

Winstrol (dépôt de winstrol, winstrol oral) est un nom de marque de stéroïde anabolisant très populaire appelé stanozolol, qui est un dérivé de DHT (dihydrotestostérone). Il a un faible rapport androgène et donc une faible possibilité d'aromatisation et d'effets secondaires liés aux œstrogènes.

It’s primarily usage in bodybuilding is cutting (relief) cycles. However, winstrol est largement utilisé non seulement par les culturistes mais aussi par les athlètes non culturistes tels que les coureurs, les cyclistes, les joueurs de football, les joueurs de football ou de hockey et les combattants de toutes sortes (kick-boxers par exemple); c'est-à-dire dans les sports où il faut être rapide mais pas trop lourd, car il vous procure une masse maigre et améliore votre force sans gagner trop de muscles.

Stanozolol is, one of the chemicals, which allowed amazing results to famous runner and simply exceptional athlete Ben Johnson. This substance provided him with a noticeable gain in muscle mass and relief, which could be perfect even for professional bodybuilder.

So, winstrol is a very effective steroid when used properly. It is important to distinguish between two forms of winstrol-stanozolol,  first is long-acting injectable version called winstrol-depot. Second is short-acting oral one (winstrol oral). Winstrol depot is more effective and thus preferred by most athletes.

The main usage of Winstrol (Winstrol Depot) in bodybuilding is preparation for a competition. When complemented by a proper calorie-rich and protein-rich diet,  Winstrol Depot provides the muscles with firmness and elasticity. Unfortunately, due to its low androgenic component, it is unable to protect the athlete from damages to muscle tissue. The absence of androgenic effect is compensated by stacking with Parabolan. The combination of injectable Winstrol 50 mg per day and Parabolan  2-3 amps / week is “a combination of top championships”.

Winstrol est bon non seulement pour la préparation d'une compétition, mais aussi pour la phase de groupage. En raison d'une faible rétention d'eau, des gains de poids rapides avec Winstrol sont peu probables. Il fournit une quantité plutôt modérée de masse maigre et sèche, qui se conserve après la fin du cycle.

Les injections de Winstrol dans certains groupes musculaires gagnent en popularité car les athlètes ont remarqué que cela conduisait à une croissance accélérée des muscles affectés.

 

Dosage et utilisation

Injectable version is just slightly more efficient than the oral one and it’s not being destroyed by the liver. Because of this oral Winstrol requires a little bit higher dosages, however, most of athletes underdose it due to gastroenterial pain and increased liver values – oral winstrol is liver-toxic. So, here is where the myth of superiority of injectable winstrol comes from. People simply can’t take equal dosages of oral version. Common  dosage of oral stanozolol is  15-30 mg / ED, daily dosage should be split on two parts – in the morning and evening during a meal, drink a liquid along with it.

La particularité du Winstrol Depot injectable est que sa substance est dissoute dans l'eau et non dans l'huile contrairement à la plupart des autres stéroïdes. Par conséquent, les intervalles entre les injections de Winstrol Depot doivent être plus courts que ceux d'autres stéroïdes à base d'huile comme Primobolan, Deca-Duraboline, Sustanon, Parabolan, etc. car sa durée de vie est beaucoup plus courte. La pratique a montré que Winstrol Depot doit être administré au moins deux fois par jour et les meilleurs résultats sont observés à une dose quotidienne de 50 mg. (300-350 mg / semaine). La dose la plus douce est de 50 mg / EOD (150 mg / semaine)

Injectez profondément dans les muscles et faites constamment tourner les taches. Cependant, si l'athlète souhaite promouvoir des injections de groupes musculaires particuliers, il doit y être fait.

 

Empilement

Winstrol (stanozolol) is all-purpose steroid, however, we should admit that in first turn it’s a cutting agent for bodybuilder and it plays rather limited role in bulking cycles. The main reason for using it in non-cutting cycles is that in limited dose it can lower SHBG, which, in turn, increases the amount of free testosterone in the body

Depending on the level of the athlete, one usually takes 50 mg of long-acting Winstrol /ED or EOD and Parabolan 76 mg/ every 1 – 3 days. Although there is no scientific evidence in favor of special interaction between Winstrol Depot and Parabolan, it’s very likely that a synergistic effect appears basing on real-world evidence. Other steroids that well stack with winstrol during pre-competition (cutting) cycle are Masterolone, Boldenone, Halotestin, Oxandrolone (anavar), Testosterone propionate, Primobolan and human growth hormone (HGH).

Bodybuilders who want to build up strength and mass often combine Winstrol injectable with Dianabol, Anadrol 50 (Anapolon, Oxymetholone), Testosterone,(long-acting) and Deca-Durabolin. With the combination of Anadrol 50 100 mg  / ED, 50 mg Winstrol depot 50 mg / ED and 400 mg of Deca / week athlete is slowly coming to the ambitious results.

Les athlètes âgés et les novices en stéroïdes peuvent réaliser de bons progrès avec Winstrol depot et Deca-Durabolin ou Winstrol depot et Primobolan

 

Cycle 0

winstrol depot 50 mg / ED is a cutting stack. Some people may do 50 mg/Ed, it’s more aggressive.

 

Cycle  1:

Winstrol 100-150 mf / semaine + primobolan 200-300 mg / semaine pendant 6 semaines en phase de coupe APRÈS le cycle régulier de déca-dianabol

 

Cycle 2

Oxandrolone (anavar) 20-30 mg / ED + winstrol 150 mg / semaine + clenbutérol 120 mg / ED pendant 12 semaines; prabolan 152-228 mg / semaine pendant les 8 premières semaines; proviron 300 mg / semaine + cytomel augmentation de 25 à 100 mg / semaine pendant les semaines 9-12

 

Cycle 3

Winstrol 150 mg / w + parabolan 152 mg / w

 

Cycle 4

winstrol (150 mg / w) + dianabol (20-30 mg / ED) + test propionate (150 mg / w) pendant 8-10 semaines + clen à la fin

 

Cycle 5

winstrol 50-100 mg / w + déca 300-200 mg / w

 

Cycle 6

winstrol oral 40-60 mg / ED + équilibre (boldabol) 100-200 mg / w

 

Cycle 7

winstrol + trenbolone + clenbutérol - cycle de soulagement pour les novices.

 

Cycle 8

primobolan 200-300 mg / w + winstrol 150-300 mg / w + oxandrolone 20-60 mg / ED + clenbutérol + PCT (tamo et HCG) - soulagement pour les utilisateurs avancés

 

Cycle 9

boldenone 300 mg / w + winstrol oral 40 mg / ED + nandrolone phenilpropionate 300 mg / w - soulagement pour les utilisateurs avancés

 

Temps de détection

Stanozolol oral - 3 semaines
Stanozolol injectable (dépôt winstrol) - 3 mois

 

Side effects and PCT (Post Cycle Therapy) with winstrol / stanozolol

Only small number of athletes report water retention or  other negative effects. However, one should be aware that oral winstrol can be toxic to the liver in excessive dosages.

 

Les autres effets indésirables non androgéniques pouvant survenir sont: des maux de tête, des spasmes musculaires, dans de rares cas une hypertension artérielle peut survenir. La possibilité de lésions hépatiques sous forme de Winstrol injectable est très faible, mais toujours à des doses élevées peut augmenter les valeurs hépatiques.

 

Because the Winstrol Depot is dissolved in the water, injection,  in common is more painful comparing to oil-based gear and have to be taken more frequently. This leads to another negative effect – scar tissue on the often injection spots, which cause athletes t inject not only  into buttocks but also to shoulders, legs or even calves. Athletes wishing to avoid this take Winstrol Depot twice a week for 2-3ml. This decreases effectiveness but decreases pain and prevents scar tissue appearance.

Comme avec la plupart des autres stéroïdes, le winstrol supprime les niveaux hormonaux naturels, mais pas dans cette extension comme beaucoup d'autres. Exécuter de la testostérone dans un cycle contenant du Winstrol permet d'éviter un éventuel dysfonctionnement sexuel.

After winstrol cycle is over it’s necessary to do PCT: First week: 40mg of tamoxifen or 100mg clomiphen / ED or combo of both. One-two more weeks:  20mg of tamoxifen or 50mg clomiphen or combo of both.

 

Usage féminin

It’s one of the few substances, which could be used more or less safely by females in low dosages because it has more anabolic properties than androgenic ones. But occasionally winstrol can cause virilization, even this small androgenic component may, become noticeable for women with a dose of only 50 mg per week. And troubles are almost guaranteed for female athletes with a dosage of 100 mg / week. Despite Winstrol moves out quickly, it can cause undesired accumulation of androgens in the female body, which cause virilization effects such as deep voice, hair growth, hypersexuality, etc. (something similar happens to some of natural brunettes). However, ambitious female athletes still use it 50 mg / EOD disregarding all side effects.

Normally, female athlete can tolerate around 5-10mg of stanosolol per day, which perfectly fits for oral winstrol usage

 

Oral Winstrol

As it has been already mentioned, injectable version is more efficient than the oral one but this is mostly because oral winstrol is used in lower dosages than injectable one and athletes simply don’t receive enough substance. If you take 50 mg of oral winstrol a day, the results will be almost par with 50 mg of Winstrol depot, however, you may have problems with stomach and liver.

D'autre part, le winstrol oral est un bon équipement pour les femmes, elles ne peuvent faire que 5 à 10 mg / ED et donc les effets négatifs décrits ci-dessus ne se produiront pas. De plus, le winstrol oral permet de diviser la dose quotidienne en deux parties égales,

 

Faux Winstrol

Due to popularity of winstrol there are many fakes on the market. The first thing to mention is that British Dragon winstrol depot and stanozolol (oral winstrol)  is no longer manufactured since they got busted, It might be still in circulation till the end of 2011 but anything with manufacture date after 2008 is a fake.

 

Brève description du stanozolol:
Activité: 48 heures
Classification: stéroïde anabolisant / androgène
Dose: Hommes 25-100 mg / jour
Acné: rare
Rétention d'eau: rare
Hypertension artérielle: rare
Hépatotoxicité: Oui, il est alcalinisé 17-Alpha
Aromatisation: Non, c'est un dérivé de DHT
Conversion DHT: Non
Diminuer la fonction HPTA: faible


Buy online cheap winstrol (stanozolol)

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Deca Durabolin [Nandrolone Decanoate] review

Deca-durabolin is Organon tradename for extremely popular and widely used bulking anabolic steroid, which contains substance called nandrolone decanoate. Another less known but still very efficient nandrolone ester is phenylpropionate (Durabolin). There are dozens of different brand names like Retabolin or Nandrolona-D, but we’ll call it “Deca” for short.

With proper diet and usage it reduces body fat, provides great strength and size gains and does not cause problems with the liver. At the same time it increases hematorcrit level and bone density, therefore having positive effect not only in sport but also in treating certain forms of cancer,  anemia and osteoporosis, which is very important for females during menopause.

Main advantage of deca-durabolin is good anabolic effect and increased protein synthesis in muscle cells, which leads to superb muscle growth. However, protein building effect will occur in the body only if sufficient amount of calories and proteins is supplied, otherwise good results cannot be obtained.

Since Nandrolone stores more water in the connective tissues, it can temporarily ease or even cure existing pain in joints. This process is called water retention, which is more considerable comparing to using of injectable testosterones and it also leads to bigger outlook. Therefore, athletes who complain about pain in the shoulders, elbows, knees, can safely train with the aid of Déca-Durabolin.

Dosage of 400 mg per week also helps to accelerate recovery due to moderate androgenic effect of déca.

Dosage et utilisation

Athletes use Déca-Durabolin for muscle buildup and during bulking part of preparation for a contest because Deca promotes protein synthesis although other side of coin is water retention in the body. The dosage for men lies between 200 – 600 mg per week, the most common option is 400 mg. Scientific studies have shown that the best results can be achieved with 4 mg per 1 kg (2 mg/pound) of body weight.

At a dosage below 200 mg per week, the anabolic effects is very weak. 200-600 mg – anabolic effects growth rapidly with dosage. If dosage exceeds 600 mg / week, anabolic effect is still no more than effect of 600 mg  but side effects start killing all positive ones, so this dosage is not advisable. 1000mg is not better than 600 mg.

Beginners should use 200 mg/week, max 400 mg/week.

Inject deca-duraboline (nandrolone decanoate) in equal dosages twice a week deep in muscles, preferably buttocks.

Empilement

Déca-Durabolin is an effective steroid, which not only gives the desired results, but also goes well with other steroids in order to achieve a more rapid effect.

For muscle-build purposes déca very well combines with Dianabol (methandienone) et Testostérone. The classic Deca / Dianabol combo is for fast and strong gaining of muscle mass. Most athletes usually take 15 – 40 mg Dianabol per day and 200 – 400 mg Deca per week. Even faster results can be achieved with 400 mg of Deca / week and 500 mg Sustanon 250 / week.

Enormous gain in strength and muscle size could be achieved with 400 mg Deca, 500 mg Sustanon 250 / week and 30 mg of Dianabol /  day.

Professional users can combine déca with anapolon (anadrol/oxydrol) instead of dianabol.

A good startup stack is deca (deca durabolin, nandrolone decanoate) 400 mg/week + dianabol (danabol, naposim, methandienone) 40-50 mg/day. Length of cycle is 8 weeks. Don’t forget about anti-estrogen from the week 3 and 1 week after the cycle – tamoxifen or clomid (1 tab ED). For this cycle we advice you also using LIV-52 for liver protection.

Using anti-estrogen for this cycle is important. Also, it restores natural test production. Using liv-52 is not absolutely necessary but makes this cycle completely safe.

For the whole 8 week cycle athlete needs: Deca: 3200mg, Dianabol” ~ 2240-2800 mg, Tamoxifen/Clomid: 50 tabs, Liv-52: 1 bottle.

Although Deca-Durabolin is not an optimal steroid when preparing for competition due to excessive water storage many athletes still achieve good results during this phase of preparation if they have suficient time to “dry” afterwards. Alternatively, athlete may switch from long-acting déca to faster-acting ester duraboline (nandrolon-phenilpropionate) and thus avoid extra water retention.

Classic preparatory stack for contest is following: Déca-Durabolin 400 mg/week, Winstrol 50 mg/day, Parabolan 228 mg/week (every ampule contains 76 mg of substance) , and  Anavar (Oxandrolone) 25-30 mg/day (10 mg tabs).

Injectable Nandrolone (Deca-Durabolin) has no negative effect on the liver even if used for years UNLESS OVERDOSED. It can even be used by persons with liver diseases.

Even deca/dianabol combo negative effect on the liver could be eliminated quickly after user discontinues dianabol part.

Relatively  safe stack is a combination of Deca Durabolin 400 mg/week with Andriol 280mg / day. Both of these products are liver-friendly. However, PCT is still necessary.

Temps de détection

If doping tests are expected it is better to refrain from taking Deca Durabolin because its traces remain in the body for quite a long time.

In certain cases Nandrolone Decanoate (deca-duraboline) is detectable for up to 18 months (1 and 1/2 year) although this is an extreme occasion.

Effets secondaires et PCT (Post Cycle Therapy) avec deca

It’s not advisable to use nandrolone for the athletes below 21 y.o. and especially in prepubescent period because it might be very harmful for their health.

Due to relatively low androgenic ratio, aromatization (i.e. conversion into estrogen) with Deca used standalone appears only at a dose of 400 mg per week, although this does not mean that one should neglect it completely. Aromatization appears for all steroids with androgenic component and may result in growing breast (so-called “bitch tits”), female-patter fat deposits, etc., so it’s much better to avoid such side effects by using anti-estrogen (see below).

Androgen-related side effects are unlikely to appear at dosages up to 400 mg but still should be considered. They include high blood pressure, blood clotting, which leads to frequent bleeding from the nose and a long healing of scratches, as well as increased production of the sebaceous gland and occasional acne. Some athletes also report headaches and sexual overstimulation. When very high doses are used over a prolonged period they can inhibit spermatogenesis. I.e., testes produce less testosterone because Deca-Durabolin, like almost all steroids, inhibits the release of gonadotropins from the hypophysis. To prevent this using of clomiphen/tamoxifen AFTER the cycle is must-do requirement.

Another common side effect is excessive water retention, which is not that bad in certain occasions, for instance pain in joints, but most athletes still want to avoid it.

Aromatization and partially water retention could be eliminated by use of proviron and tamoxifen (zymoplex, novadex, cytotam) or clomiphen. Take 1 tab of clomiphen/tamoxifen during the cycle, 3 tabs for the first day after it  and 2 tabs / ED (every day) for two-three weeks afterwards. Proviron should be added in case of “heavy” cycle when action of tamo/clom is not sufficient.

Usage féminin

One of classic female stacks is Deca + Primobolan + winstrol depot or it’s variances Deca+oral primo / Deca+oral winstrol

Deca dosage up to 100 mg per week is normally quite safe for women. With higher dosages androgen-related side effects may occur. This is called virilization – irreversible appearing of deep “men’s” voice, increased growth of body hair, acne, increased libido, clitorishypertrophy.

To avoid skin problems female athletes may use more fast-acting duraboline (nandrolon-phenilpropionate). 50-100 mg of Duraboline per week could be a good choice for them who are very sensetive to androgenic side effects.

But in most cases even long-acting Deca 50-100 mg/week is OK and female athletes may combine it with Anavar 10 mg/ ED (every day). Both compounds, when taken in a low dosage, have only slight androgenic component so that virilization side effects only rarely occur. Deca provides substantial muscle growth and Anavar provides measurable strength gain with very low water retention. Switching from deca to primobolan in this stack will make cycle even safer but gains will be lower, too.

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