Anapolon [Anadrol 50] (Oxymetholone) Balkan Pharmaceuticals Ltd. (Moldova)
Anapolon [Anadrol 50] (Oxymetholone) Abdi Ibrahim (Turkey)
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- Activity: about 16 hours
- Classification: oral Anabolic/Androgenic Steroids
- Doses: Men only 50-150 mg/day
- Acne: Yes
- Water Retention: High
- High blood pressure: Yes
- Hepatotoxicity: Medium
- Aromatization: No
- DHT conversion: Derived from DHT
- Suppression of HPTA: High
- Detection time – up to 3 months
Oxymetholone (Anadrol 50, Anapolon) was produced in 1960 by Syntex company. Since the drug can increase the number of erythrocytes, its first medical application was to treat anemia. Anapolon has been used for treatment of anemia for a long time until erythropoietin was synthesized. However, since the drug can cause rapid mass gain, it found its place in bodybuilding.
A beginner can gain up to 8-12kg of mass with just 1-2 tabs a day for less than 6 weeks. Most of this gained mass is due to water retention. Actually, Oxymetholone is not for building mass, but for lubricating connective tissues, to increase their elasticity and prevent ligament ruptures. Besides it significantly increase strength. Therefore it is very popular among weight lifters and those athletes who have problems with joints and ligaments. It is recommended to use tamoxifen + clomid during your cycle.
It is important to note that Oxymetholone is not an aromatizable steroid, since it was derived from dihydrotestosterone which has non-aromatizable structure. However, it possesses some progestogenic activity, just like nandrolone.
Also, due to its progestogenic activity, one cannot use aromatase inhibitors along with it, but only antagonists of estrogen receptors such as tamoxifen and clomid. Arimidex and similar drugs are useless in this case, since there is no aromatization.
Since Oxymetholone is a very strong androgen, it can cause such side effects as oily skin, acne, increased hair growth on the body and face.
Due to its very high androgenicity, the drug is not recommended for women, as it can cause virilization, even before you take any measures.
It should be noted that small amounts of Oxymetholone are converted to dihydrotestosterone, but this does not occur through exposure to 5-alpha reductase.
Structurally Oxymetholone is a dihydrotestosterone, with a 17-methyl radical attached at the position, and at the position of the 2-hydroxymethylene group.
Like all 17 alpha alkylated steroids, Oxymetholone, taken in high doses, can potentially cause damage to the liver. This is further aggravated by the fact that it is produced in a dosage much higher than the dosage in which dianabol or stanazolol is released.
This dosage is explained by the fact that, unlike other steroids, it binds poorly to androgen receptors. For medical purposes, the dosage of Oxymetholone should be 1-5 mg per kilogram of patient weight.
However, athletes do not need such high dosages, so 50-150mg per day for 4-6 weeks would be enough. During the cycle it is advisable to monitor the liver. Also you should control blood pressure due to the high water retention.
After discontinuation of the drug, there may be a very sharp loss of gained weight. Since Oxymetholone causes a strong suppression of endogenous testosterone, it is recommended to start taking CHG before the end of a cycle, taking clomid and tamoxifen at the same time.
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